Association between maternal sleep practices and late stillbirth - findings from a stillbirth case-control study

Alexander EP Heazell; Minglan Li; J Budd; JMD Thompson; T Stacey; Robin S Cronin; Bill Martin; Devender Roberts; EA Mitchell; LME McCowan

doi:10.1111/1471-0528.14967

Association between maternal sleep practices and late stillbirth - findings from a stillbirth case-control study

Alexander EP Heazell, Minglan Li, J Budd, JMD Thompson, T Stacey, Robin S Cronin, Bill Martin, Devender Roberts, EA Mitchell, LME McCowan

Methodologies

Research output: Contribution to journal › Article › peer-review

73 Citations (Scopus)

Abstract

Objective: To report maternal sleep practices in women who experienced a stillbirth compared with controls with ongoing live pregnancies at similar gestation.Design: Prospective case‐control study.Setting: Forty‐one maternity units in the United Kingdom.Population: Women who had a stillbirth after ≥ 28 weeks’ gestation (n = 291) and women with an ongoing pregnancy at the time of interview (n = 733).Methods: Data were collected using an interviewer‐administered questionnaire that included questions on maternal sleep practices before pregnancy, in the four weeks prior to, and on the night before the interview/stillbirth.Main outcome measures: Maternal sleep practices during pregnancy.Results: In multivariable analysis, supine going‐to‐sleep position the night before stillbirth had a 2.3‐fold increased risk of late stillbirth [adjusted Odds Ratio (aOR) 2.31, 95% CI 1.04–5.11] compared with the left side. In addition, women who had a stillbirth were more likely to report sleep duration less than 5.5 hours on the night before stillbirth (aOR 1.83, 95% CI 1.24–2.68), getting up to the toilet once or less (aOR 2.81, 95% CI 1.85–4.26), and a daytime nap every day (aOR 2.22, 95% CI 1.26–3.94). No interaction was detected between supine going‐to‐sleep position and a small‐for‐gestational‐age infant, maternal body mass index, or gestational age. The population‐attributable risk for supine going‐to‐sleep position was 3.7% (95% CI 0.5–9.2).Conclusions: This study confirms that supine going‐to‐sleep position is associated with late stillbirth. Further work is required to determine whether intervention(s) can decrease the frequency of supine going‐to‐sleep position and the incidence of late stillbirth.

Original language	English
Pages (from-to)	254-262
Number of pages	9
Journal	BJOG: An International Journal of Obstetrics and Gynaecology
Volume	125
Issue number	2
DOIs	https://doi.org/10.1111/1471-0528.14967
Publication status	Published - 1 Jan 2018

Keywords

Maternal sleep position
Modifiable risk factors
Sleep duration
Stillbirth

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/1471-0528.14967Licence: CC BY-NC-ND

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Heazell, A. EP., Li, M., Budd, J., Thompson, JMD., Stacey, T., Cronin, R. S., Martin, B., Roberts, D., Mitchell, EA., & McCowan, LME. (2018). Association between maternal sleep practices and late stillbirth - findings from a stillbirth case-control study. BJOG: An International Journal of Obstetrics and Gynaecology, 125(2), 254-262. https://doi.org/10.1111/1471-0528.14967

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title = "Association between maternal sleep practices and late stillbirth - findings from a stillbirth case-control study",

abstract = "Objective: To report maternal sleep practices in women who experienced a stillbirth compared with controls with ongoing live pregnancies at similar gestation.Design: Prospective case‐control study.Setting: Forty‐one maternity units in the United Kingdom.Population: Women who had a stillbirth after ≥ 28 weeks{\textquoteright} gestation (n = 291) and women with an ongoing pregnancy at the time of interview (n = 733).Methods: Data were collected using an interviewer‐administered questionnaire that included questions on maternal sleep practices before pregnancy, in the four weeks prior to, and on the night before the interview/stillbirth.Main outcome measures: Maternal sleep practices during pregnancy.Results: In multivariable analysis, supine going‐to‐sleep position the night before stillbirth had a 2.3‐fold increased risk of late stillbirth [adjusted Odds Ratio (aOR) 2.31, 95% CI 1.04–5.11] compared with the left side. In addition, women who had a stillbirth were more likely to report sleep duration less than 5.5 hours on the night before stillbirth (aOR 1.83, 95% CI 1.24–2.68), getting up to the toilet once or less (aOR 2.81, 95% CI 1.85–4.26), and a daytime nap every day (aOR 2.22, 95% CI 1.26–3.94). No interaction was detected between supine going‐to‐sleep position and a small‐for‐gestational‐age infant, maternal body mass index, or gestational age. The population‐attributable risk for supine going‐to‐sleep position was 3.7% (95% CI 0.5–9.2).Conclusions: This study confirms that supine going‐to‐sleep position is associated with late stillbirth. Further work is required to determine whether intervention(s) can decrease the frequency of supine going‐to‐sleep position and the incidence of late stillbirth.",

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Heazell, AEP, Li, M, Budd, J, Thompson, JMD, Stacey, T, Cronin, RS, Martin, B, Roberts, D, Mitchell, EA & McCowan, LME 2018, 'Association between maternal sleep practices and late stillbirth - findings from a stillbirth case-control study', BJOG: An International Journal of Obstetrics and Gynaecology, vol. 125, no. 2, pp. 254-262. https://doi.org/10.1111/1471-0528.14967

TY - JOUR

T1 - Association between maternal sleep practices and late stillbirth - findings from a stillbirth case-control study

AU - Heazell, Alexander EP

AU - Li, Minglan

AU - Budd, J

AU - Thompson, JMD

AU - Stacey, T

AU - Cronin, Robin S

AU - Martin, Bill

AU - Roberts, Devender

AU - Mitchell, EA

AU - McCowan, LME

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Objective: To report maternal sleep practices in women who experienced a stillbirth compared with controls with ongoing live pregnancies at similar gestation.Design: Prospective case‐control study.Setting: Forty‐one maternity units in the United Kingdom.Population: Women who had a stillbirth after ≥ 28 weeks’ gestation (n = 291) and women with an ongoing pregnancy at the time of interview (n = 733).Methods: Data were collected using an interviewer‐administered questionnaire that included questions on maternal sleep practices before pregnancy, in the four weeks prior to, and on the night before the interview/stillbirth.Main outcome measures: Maternal sleep practices during pregnancy.Results: In multivariable analysis, supine going‐to‐sleep position the night before stillbirth had a 2.3‐fold increased risk of late stillbirth [adjusted Odds Ratio (aOR) 2.31, 95% CI 1.04–5.11] compared with the left side. In addition, women who had a stillbirth were more likely to report sleep duration less than 5.5 hours on the night before stillbirth (aOR 1.83, 95% CI 1.24–2.68), getting up to the toilet once or less (aOR 2.81, 95% CI 1.85–4.26), and a daytime nap every day (aOR 2.22, 95% CI 1.26–3.94). No interaction was detected between supine going‐to‐sleep position and a small‐for‐gestational‐age infant, maternal body mass index, or gestational age. The population‐attributable risk for supine going‐to‐sleep position was 3.7% (95% CI 0.5–9.2).Conclusions: This study confirms that supine going‐to‐sleep position is associated with late stillbirth. Further work is required to determine whether intervention(s) can decrease the frequency of supine going‐to‐sleep position and the incidence of late stillbirth.

AB - Objective: To report maternal sleep practices in women who experienced a stillbirth compared with controls with ongoing live pregnancies at similar gestation.Design: Prospective case‐control study.Setting: Forty‐one maternity units in the United Kingdom.Population: Women who had a stillbirth after ≥ 28 weeks’ gestation (n = 291) and women with an ongoing pregnancy at the time of interview (n = 733).Methods: Data were collected using an interviewer‐administered questionnaire that included questions on maternal sleep practices before pregnancy, in the four weeks prior to, and on the night before the interview/stillbirth.Main outcome measures: Maternal sleep practices during pregnancy.Results: In multivariable analysis, supine going‐to‐sleep position the night before stillbirth had a 2.3‐fold increased risk of late stillbirth [adjusted Odds Ratio (aOR) 2.31, 95% CI 1.04–5.11] compared with the left side. In addition, women who had a stillbirth were more likely to report sleep duration less than 5.5 hours on the night before stillbirth (aOR 1.83, 95% CI 1.24–2.68), getting up to the toilet once or less (aOR 2.81, 95% CI 1.85–4.26), and a daytime nap every day (aOR 2.22, 95% CI 1.26–3.94). No interaction was detected between supine going‐to‐sleep position and a small‐for‐gestational‐age infant, maternal body mass index, or gestational age. The population‐attributable risk for supine going‐to‐sleep position was 3.7% (95% CI 0.5–9.2).Conclusions: This study confirms that supine going‐to‐sleep position is associated with late stillbirth. Further work is required to determine whether intervention(s) can decrease the frequency of supine going‐to‐sleep position and the incidence of late stillbirth.

KW - Maternal sleep position

KW - Modifiable risk factors

KW - Sleep duration

KW - Stillbirth

U2 - 10.1111/1471-0528.14967

DO - 10.1111/1471-0528.14967

M3 - Article

SN - 1470-0328

VL - 125

SP - 254

EP - 262

JO - BJOG: An International Journal of Obstetrics and Gynaecology

JF - BJOG: An International Journal of Obstetrics and Gynaecology

IS - 2

ER -

Association between maternal sleep practices and late stillbirth - findings from a stillbirth case-control study

Abstract

Keywords

UN SDGs

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