TY - JOUR
T1 - Association between physical activity and comorbid anxiety/depression in 46 low- and middle-income countries
AU - Ma, Ruimin
AU - Romano, Eugenia
AU - Vancampfort, Davy
AU - Firth, Joseph
AU - Stubbs, Brendon
AU - Koyanagi, Ai
N1 - Funding Information:
This research was supported by the Medical Research Council (Grant Reference: MC_PC_MR/T037806/1 and in part by the National Institute of Health Research using Official Development Assistance (ODA) funding (Grant: 17/63/130 : NIHR Global Health Research Group: Improving Outcomes in Mental and Physical Multimorbidity and Developing Research Capacity (IMPACT) in South Asia at the University of York). BS is supported by a Clinical Lectureship (ICA-CL-2017-03-001) jointly funded by Health Education England (HEE) and the National Institute for Health Research (NIHR) . Brendon Stubbs is part funded by the NIHR Biomedical Research Centre at South London and Maudsley NHS Foundation Trust. Brendon Stubbs also holds active grants with the Medical Research Council (GCRF and multimorbidity calls) and Guys and St Thomas Charity (GSTT) . JF is supported by a University of Manchester Presidential Fellowship ( P123958 ) and a UK Research and Innovation Future Leaders Fellowship ( MR/T021780/1 ) and has received honoraria / consultancy fees from Atheneum, ParachuteBH and Nirakara, independent of this work.
Funding Information:
This research was supported by the Medical Research Council (Grant Reference: MC_PC_MR/T037806/1 and in part by the National Institute of Health Research using Official Development Assistance (ODA) funding (Grant: 17/63/130: NIHR Global Health Research Group: Improving Outcomes in Mental and Physical Multimorbidity and Developing Research Capacity (IMPACT) in South Asia at the University of York). BS is supported by a Clinical Lectureship (ICA-CL-2017-03-001) jointly funded by Health Education England (HEE) and the National Institute for Health Research (NIHR). Brendon Stubbs is part funded by the NIHR Biomedical Research Centre at South London and Maudsley NHS Foundation Trust. Brendon Stubbs also holds active grants with the Medical Research Council (GCRF and multimorbidity calls) and Guys and St Thomas Charity (GSTT). JF is supported by a University of Manchester Presidential Fellowship (P123958) and a UK Research and Innovation Future Leaders Fellowship (MR/T021780/1) and has received honoraria / consultancy fees from Atheneum, ParachuteBH and Nirakara, independent of this work.
Publisher Copyright:
© 2022
PY - 2023/1/1
Y1 - 2023/1/1
N2 - Background: Evidence on the association of low physical activity (PA) with depression or anxiety is well established. Yet, evidence on the association between PA and comorbid anxiety/depression remains scarce, especially in low- and middle-income countries (LMICs). Thus, this study explored this relationship among adults aged ≥18 years from 46 LMICs. Methods: Cross-sectional, community-based data were analyzed from the World Health Survey (WHS). Multivariable multinomial logistic regression analysis was conducted to examine the association between low PA and comorbid anxiety/depression with no anxiety or depression as the base category. Results: 237,023 participants [mean (SD) age = 38.4 (16.0) years; 50.8 % female] were included in the analysis. Low PA was significantly associated with depression alone (OR = 1.33; 95%CI = 1.12–1.57) and anxiety alone (OR = 1.37; 95%CI = 1.23–1.53), while the OR was highest among those with comorbid anxiety/depression (OR = 1.75; 95%CI = 1.52–2.01). Conclusion: Low PA is associated with particularly increased odds for comorbid anxiety/depression. Increasing PA may have a beneficial effect on the prevention of comorbid anxiety/depression. However, future longitudinal research establishing the direction of this relationship is warranted.
AB - Background: Evidence on the association of low physical activity (PA) with depression or anxiety is well established. Yet, evidence on the association between PA and comorbid anxiety/depression remains scarce, especially in low- and middle-income countries (LMICs). Thus, this study explored this relationship among adults aged ≥18 years from 46 LMICs. Methods: Cross-sectional, community-based data were analyzed from the World Health Survey (WHS). Multivariable multinomial logistic regression analysis was conducted to examine the association between low PA and comorbid anxiety/depression with no anxiety or depression as the base category. Results: 237,023 participants [mean (SD) age = 38.4 (16.0) years; 50.8 % female] were included in the analysis. Low PA was significantly associated with depression alone (OR = 1.33; 95%CI = 1.12–1.57) and anxiety alone (OR = 1.37; 95%CI = 1.23–1.53), while the OR was highest among those with comorbid anxiety/depression (OR = 1.75; 95%CI = 1.52–2.01). Conclusion: Low PA is associated with particularly increased odds for comorbid anxiety/depression. Increasing PA may have a beneficial effect on the prevention of comorbid anxiety/depression. However, future longitudinal research establishing the direction of this relationship is warranted.
KW - Anxiety
KW - Depression
KW - Low- and middle-income countries
KW - Physical activity
UR - http://www.scopus.com/inward/record.url?scp=85140018163&partnerID=8YFLogxK
U2 - 10.1016/j.jad.2022.10.002
DO - 10.1016/j.jad.2022.10.002
M3 - Article
C2 - 36209777
AN - SCOPUS:85140018163
SN - 0165-0327
VL - 320
SP - 544
EP - 551
JO - Journal of Affective Disorders
JF - Journal of Affective Disorders
ER -
