Association of Pharmacogenetic Markers With Atazanavir Exposure in HIV-Infected Women

Women's Interagency HIV Study

doi:10.1002/cpt.1605

Association of Pharmacogenetic Markers With Atazanavir Exposure in HIV-Infected Women

Women's Interagency HIV Study

Diabetes

University of California, San Francisco
John H. Stroger Jr Hospital of Cook County
Georgetown University
Yeshiva University
USC University of Southern California
Johns Hopkins Bloomberg School of Public Health
Downstate Medical Center Rheumatology
University of California, Davis
King's College London
Great Ormand Street Institute for Child Health
UCL University College London
New York University

Research output: Contribution to journal › Letter › peer-review

1 Citation (Scopus)

Abstract

SORCS2 rs73208473 was recently associated with decreased atazanavir (ATV) concentration in the hair of women with seropositive HIV. Herein, we report on a pharmacogenetic study of women with seropositive HIV demonstrating a similar association between rs73208473 and dose-adjusted plasma ATV concentration in African Americans.

Original language	English
Pages (from-to)	315-318
Number of pages	4
Journal	Clinical Pharmacology and Therapeutics
Volume	107
Issue number	2
Early online date	28 Sept 2019
DOIs	https://doi.org/10.1002/cpt.1605
Publication status	Published - 1 Feb 2020

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SDG 3 Good Health and Well-being

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10.1002/cpt.1605

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title = "Association of Pharmacogenetic Markers With Atazanavir Exposure in HIV-Infected Women",

abstract = "SORCS2 rs73208473 was recently associated with decreased atazanavir (ATV) concentration in the hair of women with seropositive HIV. Herein, we report on a pharmacogenetic study of women with seropositive HIV demonstrating a similar association between rs73208473 and dose-adjusted plasma ATV concentration in African Americans.",

author = "Bani Tamraz and Yong Huang and French, \{Audrey L.\} and Seble Kassaye and Kathryn Anastos and Nowicki, \{Marek J.\} and Stephen Gange and Gustafson, \{Deborah R.\} and Peter Bacchetti and Greenblatt, \{Ruth M.\} and Hysi, \{Pirro G.\} and Aouizerat, \{Bradley E.\} and \{Women's Interagency HIV Study\}",

year = "2020",

month = feb,

day = "1",

doi = "10.1002/cpt.1605",

language = "English",

volume = "107",

pages = "315--318",

journal = "Clinical Pharmacology and Therapeutics",

issn = "0009-9236",

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TY - JOUR

T1 - Association of Pharmacogenetic Markers With Atazanavir Exposure in HIV-Infected Women

AU - Tamraz, Bani

AU - Huang, Yong

AU - French, Audrey L.

AU - Kassaye, Seble

AU - Anastos, Kathryn

AU - Nowicki, Marek J.

AU - Gange, Stephen

AU - Gustafson, Deborah R.

AU - Bacchetti, Peter

AU - Greenblatt, Ruth M.

AU - Hysi, Pirro G.

AU - Aouizerat, Bradley E.

AU - Women's Interagency HIV Study

PY - 2020/2/1

Y1 - 2020/2/1

N2 - SORCS2 rs73208473 was recently associated with decreased atazanavir (ATV) concentration in the hair of women with seropositive HIV. Herein, we report on a pharmacogenetic study of women with seropositive HIV demonstrating a similar association between rs73208473 and dose-adjusted plasma ATV concentration in African Americans.

AB - SORCS2 rs73208473 was recently associated with decreased atazanavir (ATV) concentration in the hair of women with seropositive HIV. Herein, we report on a pharmacogenetic study of women with seropositive HIV demonstrating a similar association between rs73208473 and dose-adjusted plasma ATV concentration in African Americans.

UR - https://www.scopus.com/pages/publications/85073961740

U2 - 10.1002/cpt.1605

DO - 10.1002/cpt.1605

M3 - Letter

C2 - 31562781

AN - SCOPUS:85073961740

SN - 0009-9236

VL - 107

SP - 315

EP - 318

JO - Clinical Pharmacology and Therapeutics

JF - Clinical Pharmacology and Therapeutics

IS - 2

ER -

Association of Pharmacogenetic Markers With Atazanavir Exposure in HIV-Infected Women

Abstract

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