Asymmetric division of Drosophila neural progenitors

W Chia; X H Yang

Asymmetric division of Drosophila neural progenitors

W Chia, X H Yang

King's College London

Research output: Contribution to journal › Literature review › peer-review

45 Citations (Scopus)

Abstract

Asymmetric division is a fundamental mechanism for generating cellular diversity. Studies on Drosophila neural progenitors have provided valuable insight into how evolutionarily conserved protein cassettes may be differentially deployed in different developmental contexts to mediate asymmetric divisions. Recent findings also suggest possible mechanisms by which the processes of cell-cycle progression, neuronal lineage development and asymmetric divisions may be integrated.

Original language	English
Pages (from-to)	459 - 464
Number of pages	6
Journal	Current Opinion in Genetics and Development
Volume	12
Issue number	4
Publication status	Published - 1 Aug 2002

Cite this

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title = "Asymmetric division of Drosophila neural progenitors",

abstract = "Asymmetric division is a fundamental mechanism for generating cellular diversity. Studies on Drosophila neural progenitors have provided valuable insight into how evolutionarily conserved protein cassettes may be differentially deployed in different developmental contexts to mediate asymmetric divisions. Recent findings also suggest possible mechanisms by which the processes of cell-cycle progression, neuronal lineage development and asymmetric divisions may be integrated.",

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AB - Asymmetric division is a fundamental mechanism for generating cellular diversity. Studies on Drosophila neural progenitors have provided valuable insight into how evolutionarily conserved protein cassettes may be differentially deployed in different developmental contexts to mediate asymmetric divisions. Recent findings also suggest possible mechanisms by which the processes of cell-cycle progression, neuronal lineage development and asymmetric divisions may be integrated.

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EP - 464

JO - Current Opinion in Genetics and Development

JF - Current Opinion in Genetics and Development

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