Asymmetric palladium catalysed allylic substitution using phosphorus containing oxazoline ligands

Graham J. Dawson; Christopher G. Frost; Jonathan M.J. Williams; Steven J. Coote

doi:10.1016/S0040-4039(00)93403-8

Asymmetric palladium catalysed allylic substitution using phosphorus containing oxazoline ligands

Graham J. Dawson^*, Christopher G. Frost, Jonathan M.J. Williams, Steven J. Coote

^*Corresponding author for this work

Chemistry

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Abstract

A series of new phosphorus-containing oxazoline ligands has been developed. The use of these ligands for asymmetric palladium catalysed allylic substitution of 1,3-diphenylprop-2-enyl-1-acetate 12 with the sodium salt of dimethylmalonate has been achieved with 90 - 94% ee and 88 - 99% yield.

Original language	English
Pages (from-to)	3149-3150
Number of pages	2
Journal	TETRAHEDRON LETTERS
Volume	34
Issue number	19
DOIs	https://doi.org/10.1016/S0040-4039(00)93403-8
Publication status	Published - 7 May 1993

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title = "Asymmetric palladium catalysed allylic substitution using phosphorus containing oxazoline ligands",

abstract = "A series of new phosphorus-containing oxazoline ligands has been developed. The use of these ligands for asymmetric palladium catalysed allylic substitution of 1,3-diphenylprop-2-enyl-1-acetate 12 with the sodium salt of dimethylmalonate has been achieved with 90 - 94% ee and 88 - 99% yield.",

author = "Dawson, {Graham J.} and Frost, {Christopher G.} and Williams, {Jonathan M.J.} and Coote, {Steven J.}",

year = "1993",

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T1 - Asymmetric palladium catalysed allylic substitution using phosphorus containing oxazoline ligands

AU - Dawson, Graham J.

AU - Frost, Christopher G.

AU - Williams, Jonathan M.J.

AU - Coote, Steven J.

PY - 1993/5/7

Y1 - 1993/5/7

N2 - A series of new phosphorus-containing oxazoline ligands has been developed. The use of these ligands for asymmetric palladium catalysed allylic substitution of 1,3-diphenylprop-2-enyl-1-acetate 12 with the sodium salt of dimethylmalonate has been achieved with 90 - 94% ee and 88 - 99% yield.

AB - A series of new phosphorus-containing oxazoline ligands has been developed. The use of these ligands for asymmetric palladium catalysed allylic substitution of 1,3-diphenylprop-2-enyl-1-acetate 12 with the sodium salt of dimethylmalonate has been achieved with 90 - 94% ee and 88 - 99% yield.

UR - http://www.scopus.com/inward/record.url?scp=0027196559&partnerID=8YFLogxK

U2 - 10.1016/S0040-4039(00)93403-8

DO - 10.1016/S0040-4039(00)93403-8

M3 - Article

AN - SCOPUS:0027196559

SN - 0040-4039

VL - 34

SP - 3149

EP - 3150

JO - TETRAHEDRON LETTERS

JF - TETRAHEDRON LETTERS

IS - 19

ER -

Asymmetric palladium catalysed allylic substitution using phosphorus containing oxazoline ligands

Abstract

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