Atherosclerosis and autoimmunity

P A Gordon, J George, M A Khamashta, D Harats, G Hughes, Y Shoenfeld

Research output: Contribution to journalLiterature reviewpeer-review

37 Citations (Scopus)

Abstract

Novel risk factors for the progression of atherosclerosis such as C-reactive protein (CRP) and adhesion molecules have stimulated much recent interest in the role of inflammation in atherosclerotic disease. There is also evidence emerging that autoimmunity may have a role in the pathogenesis of atherosclerosis. in this article we explore the evidence for the role of autoimmunity in human atherosclerosis, both in the general population and in the context of the antiphospholipid syndrome. In particular we will focus on several autoantigens, review the evidence for their role in the process of atherosclerosis and the nature of the immune responses.
Original languageEnglish
Pages (from-to)249 - 252
Number of pages4
JournalLupus
Volume10
Issue number4
Publication statusPublished - 2001

Fingerprint

Dive into the research topics of 'Atherosclerosis and autoimmunity'. Together they form a unique fingerprint.

Cite this