TY - JOUR
T1 - Autism Spectrum Disorder and Mental Health Problems: Patterns of Difficulties and Longitudinal Trajectories in a Population-Based Twin Sample
AU - Colvert, Emma
AU - Simonoff, Emily
AU - Capp, Simone
AU - Ronald, Angelica
AU - Bolton, Patrick
AU - Happe, Francesca
N1 - Funding Information:
The authors would like to thank the TEDS and SR Study families for their continued support with this research. The authors would also like to thank the rest of the SR Study Team for their contributions: Tracy Garnett, Nicola Gillan, Victoria Hallett, Stephanie Lietz, Catherine Stewart and Emma Woodhouse and the TEDS research team for all their assistance. The SR Study was supported by Grant G0500870 from the Medical Research Council (awarded to FH and PB). FH is funded in part by the National Institute for Health Research Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King’s College London.
Publisher Copyright:
© 2021, The Author(s).
Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2021/4/17
Y1 - 2021/4/17
N2 - There is increasing concern regarding additional psychiatric problems that co-occur with Autism Spectrum Disorder (ASD), as reflected in recent changes to diagnostic schemes. However, there remains little research with population-based samples across childhood. We report on additional problems, as measured by the Strengths and Difficulties Questionnaire, in a population-based sample of 135 twins with ASD, 55 non-ASD co-twins, and 144 comparison twins low in ASD traits. Frequencies, associated demographic factors, and changes in mental health difficulties from age 4 to 13 years are presented. Our data confirm the high rates of additional difficulties reported in previous studies, and suggest that the profile, associated risk factors and longitudinal course of additional difficulties in ASD may differ from those in typically-developing populations.
AB - There is increasing concern regarding additional psychiatric problems that co-occur with Autism Spectrum Disorder (ASD), as reflected in recent changes to diagnostic schemes. However, there remains little research with population-based samples across childhood. We report on additional problems, as measured by the Strengths and Difficulties Questionnaire, in a population-based sample of 135 twins with ASD, 55 non-ASD co-twins, and 144 comparison twins low in ASD traits. Frequencies, associated demographic factors, and changes in mental health difficulties from age 4 to 13 years are presented. Our data confirm the high rates of additional difficulties reported in previous studies, and suggest that the profile, associated risk factors and longitudinal course of additional difficulties in ASD may differ from those in typically-developing populations.
UR - http://www.scopus.com/inward/record.url?scp=85104472191&partnerID=8YFLogxK
U2 - 10.1007/s10803-021-05006-8
DO - 10.1007/s10803-021-05006-8
M3 - Article
SN - 0162-3257
JO - Journal of Autism and Developmental Disorders
JF - Journal of Autism and Developmental Disorders
ER -
