Autoimmune Hepatitis and PSC Connection

Diego Vergani; Giorgina Mieli-Vergani

doi:10.1016/j.cld.2007.11.012

Autoimmune Hepatitis and PSC Connection

Diego Vergani, Giorgina Mieli-Vergani

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

This article describes the connection between autoimmune hepatitis (AIH) and primary sclerosing cholangitis (PSC). The two conditions have chronicity, liver inflammation, and a positive autoimmune serology in common; they differ in terms of gender distribution and bile duct damage. There is evidence suggesting that AIH and PSC are immune-mediated diseases. PSC and AIH could lie within the spectrum of the same disease process. Future studies should determine how frequently AIH evolves to PSC.

Original language	English
Pages (from-to)	187 - +
Number of pages	16
Journal	Clinics in Liver Disease
Volume	12
Issue number	1
DOIs	https://doi.org/10.1016/j.cld.2007.11.012
Publication status	Published - Feb 2008

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10.1016/j.cld.2007.11.012

Cite this

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title = "Autoimmune Hepatitis and PSC Connection",

abstract = "This article describes the connection between autoimmune hepatitis (AIH) and primary sclerosing cholangitis (PSC). The two conditions have chronicity, liver inflammation, and a positive autoimmune serology in common; they differ in terms of gender distribution and bile duct damage. There is evidence suggesting that AIH and PSC are immune-mediated diseases. PSC and AIH could lie within the spectrum of the same disease process. Future studies should determine how frequently AIH evolves to PSC.",

author = "Diego Vergani and Giorgina Mieli-Vergani",

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AB - This article describes the connection between autoimmune hepatitis (AIH) and primary sclerosing cholangitis (PSC). The two conditions have chronicity, liver inflammation, and a positive autoimmune serology in common; they differ in terms of gender distribution and bile duct damage. There is evidence suggesting that AIH and PSC are immune-mediated diseases. PSC and AIH could lie within the spectrum of the same disease process. Future studies should determine how frequently AIH evolves to PSC.

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