Automated Synthesis of Cyclic Oligodeoxyribonucleotides via Phosphoramidite Method

M R  CONTE; L  MAYOL; D  MONTESARCHIO; G  PICCIALLI; C  SANTACROCE

doi:10.1080/07328319308017831

Automated Synthesis of Cyclic Oligodeoxyribonucleotides via Phosphoramidite Method

M R CONTE, L MAYOL, D MONTESARCHIO, G PICCIALLI, C SANTACROCE

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

The functionalized polyethylene glycol/polystyrene copolymer support 4 was shown to be suitable for a completely automated synthesis of small- to medium-sized cyclic oligodeoxyribonucleotides. Syntheses of the linear precursors were achieved by the phosphoramidite method, whereas the cyclization reactions were based on the phosphotriester chemistry.

Original language	English
Pages (from-to)	351-358
Number of pages	8
Journal	NUCLEOSIDES AND NUCLEOTIDES
Volume	12
Issue number	3-4
DOIs	https://doi.org/10.1080/07328319308017831
Publication status	Published - 1993

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10.1080/07328319308017831

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title = "Automated Synthesis of Cyclic Oligodeoxyribonucleotides via Phosphoramidite Method",

abstract = "The functionalized polyethylene glycol/polystyrene copolymer support 4 was shown to be suitable for a completely automated synthesis of small- to medium-sized cyclic oligodeoxyribonucleotides. Syntheses of the linear precursors were achieved by the phosphoramidite method, whereas the cyclization reactions were based on the phosphotriester chemistry.",

author = "CONTE, {M R} and L MAYOL and D MONTESARCHIO and G PICCIALLI and C SANTACROCE",

year = "1993",

doi = "10.1080/07328319308017831",

language = "English",

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journal = "NUCLEOSIDES AND NUCLEOTIDES",

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publisher = "Marcel Dekker Inc.",

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AU - CONTE, M R

AU - MAYOL, L

AU - MONTESARCHIO, D

AU - PICCIALLI, G

AU - SANTACROCE, C

PY - 1993

Y1 - 1993

N2 - The functionalized polyethylene glycol/polystyrene copolymer support 4 was shown to be suitable for a completely automated synthesis of small- to medium-sized cyclic oligodeoxyribonucleotides. Syntheses of the linear precursors were achieved by the phosphoramidite method, whereas the cyclization reactions were based on the phosphotriester chemistry.

AB - The functionalized polyethylene glycol/polystyrene copolymer support 4 was shown to be suitable for a completely automated synthesis of small- to medium-sized cyclic oligodeoxyribonucleotides. Syntheses of the linear precursors were achieved by the phosphoramidite method, whereas the cyclization reactions were based on the phosphotriester chemistry.

U2 - 10.1080/07328319308017831

DO - 10.1080/07328319308017831

M3 - Article

SN - 0732-8311

VL - 12

SP - 351

EP - 358

JO - NUCLEOSIDES AND NUCLEOTIDES

JF - NUCLEOSIDES AND NUCLEOTIDES

IS - 3-4

ER -

Automated Synthesis of Cyclic Oligodeoxyribonucleotides via Phosphoramidite Method

Abstract

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