TY - JOUR
T1 - Awareness is in the eye of the observer
T2 - Preserved third-person awareness of deficit in anosognosia for hemiplegia
AU - Besharati, Sahba
AU - Jenkinson, Paul M.
AU - Kopelman, Michael
AU - Solms, Mark
AU - Moro, Valentina
AU - Fotopoulou, Aikaterini
N1 - Funding Information:
This work was funded by an European Research Council ( ERC ) Starting Investigator Award for the project ‘The Bodily Self’ N°313755 to A.F., and a Commonwealth Scholarship, an Oppenheimer Memorial Trust Fellowship, a Neuropsychology International Fellowship Award from the British Psychological Society in conjunction with the British Neuropsychological Society, and a Wits Humanities Research Threshold Grant to S.B. SB is a CIFAR Azrieli Global Scholar in the Brain, Mind and Consciousness Program; the study was also supported by MIUR Italy (PRIN Edit. 2017; Prot. 2017N7WCLP ) to VM.
Publisher Copyright:
© 2022
PY - 2022/6/6
Y1 - 2022/6/6
N2 - In recent decades, the research traditions of (first-person) embodied cognition and of (third-person) social cognition have approached the study of self-awareness with relative independence. However, neurological disorders of self-awareness offer a unifying perspective to empirically investigate the contribution of embodiment and social cognition to self-awareness. This study focused on a neuropsychological disorder of bodily self-awareness following right-hemisphere damage, namely anosognosia for hemiplegia (AHP). A previous neuropsychological study has shown AHP patients, relative to neurological controls, to have a specific deficit in third-person perspective taking and allocentric stance (the other unrelated to the self) in higher order mentalizing tasks. However, no study has tested if verbal awareness of motor deficits is influenced by perspective-taking and centrism and identified the related anatomical correlates. Accordingly, two novel experiments were conducted with right-hemisphere stroke patients with (n = 17) and without AHP (n = 17) that targeted either their own (egocentric, experiment 1) or another stooge patients (allocentric, experiment 2) motor abilities from a first-or-third person perspective. In both experiments, neurological controls showed no significant difference in perspective-taking, suggesting that social cognition is not a necessary consequence of right-hemisphere damage. More specifically, experiment 1 found AHP patients more aware of their own motor paralysis (egocentric stance) when asked from a third compared to a first-person perspective, using both group level and individual level analysis. In experiment 2, AHP patients were less accurate than controls in making allocentric judgements about the stooge patient, but with only a trend towards significance and with no difference between perspectives. As predicted, deficits in egocentric and allocentric third-person perspective taking were associated with lesions in the middle frontal gyrus, superior temporal and supramarginal gyri, and white matter disconnections were more prominent with deficits in allocentricity. Behavioural and neuroimaging results demonstrate the intersecting relationship between bodily self-awareness and self-and-other-directed metacognition or mentalisation.
AB - In recent decades, the research traditions of (first-person) embodied cognition and of (third-person) social cognition have approached the study of self-awareness with relative independence. However, neurological disorders of self-awareness offer a unifying perspective to empirically investigate the contribution of embodiment and social cognition to self-awareness. This study focused on a neuropsychological disorder of bodily self-awareness following right-hemisphere damage, namely anosognosia for hemiplegia (AHP). A previous neuropsychological study has shown AHP patients, relative to neurological controls, to have a specific deficit in third-person perspective taking and allocentric stance (the other unrelated to the self) in higher order mentalizing tasks. However, no study has tested if verbal awareness of motor deficits is influenced by perspective-taking and centrism and identified the related anatomical correlates. Accordingly, two novel experiments were conducted with right-hemisphere stroke patients with (n = 17) and without AHP (n = 17) that targeted either their own (egocentric, experiment 1) or another stooge patients (allocentric, experiment 2) motor abilities from a first-or-third person perspective. In both experiments, neurological controls showed no significant difference in perspective-taking, suggesting that social cognition is not a necessary consequence of right-hemisphere damage. More specifically, experiment 1 found AHP patients more aware of their own motor paralysis (egocentric stance) when asked from a third compared to a first-person perspective, using both group level and individual level analysis. In experiment 2, AHP patients were less accurate than controls in making allocentric judgements about the stooge patient, but with only a trend towards significance and with no difference between perspectives. As predicted, deficits in egocentric and allocentric third-person perspective taking were associated with lesions in the middle frontal gyrus, superior temporal and supramarginal gyri, and white matter disconnections were more prominent with deficits in allocentricity. Behavioural and neuroimaging results demonstrate the intersecting relationship between bodily self-awareness and self-and-other-directed metacognition or mentalisation.
KW - Allocentrism
KW - Anosognosia
KW - Egocentrism
KW - Mentalisation
KW - Metacognition
KW - Self-awareness
KW - Social cognition
UR - http://www.scopus.com/inward/record.url?scp=85127871519&partnerID=8YFLogxK
U2 - 10.1016/j.neuropsychologia.2022.108227
DO - 10.1016/j.neuropsychologia.2022.108227
M3 - Article
C2 - 35364093
AN - SCOPUS:85127871519
SN - 0028-3932
VL - 170
JO - Neuropsychologia
JF - Neuropsychologia
M1 - 108227
ER -