Backseat drivers: Cargo adaptors and dynactin activate cytoplasmic dynein motility

Mark P. Dodding

doi:10.1038/cr.2014.115

Backseat drivers: Cargo adaptors and dynactin activate cytoplasmic dynein motility

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Abstract

Control of the activity of the microtubule motor cytoplasmic dynein 1 is essential for its function in intracellular transport. A recent paper by McKenney et al. published in Science shows that activation of processive dynein motility requires the formation of cargo adaptor-dynein-dynactin complexes.

Original language	English
Pages (from-to)	1385-1386
Number of pages	2
Journal	CELL RESEARCH
Volume	24
DOIs	https://doi.org/10.1038/cr.2014.115
Publication status	Published - 22 Aug 2014

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10.1038/cr.2014.115

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title = "Backseat drivers: Cargo adaptors and dynactin activate cytoplasmic dynein motility",

abstract = "Control of the activity of the microtubule motor cytoplasmic dynein 1 is essential for its function in intracellular transport. A recent paper by McKenney et al. published in Science shows that activation of processive dynein motility requires the formation of cargo adaptor-dynein-dynactin complexes.",

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Backseat drivers: Cargo adaptors and dynactin activate cytoplasmic dynein motility

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