Banting Memorial Lecture 2013 A life in balance: wandering the pathways of control

S. A. Amiel

doi:10.1111/dme.12351

Banting Memorial Lecture 2013 A life in balance: wandering the pathways of control

S. A. Amiel^*

^*Corresponding author for this work

Diabetes

Research output: Contribution to journal › Literature review › peer-review

3 Citations (Scopus)

Abstract

'To keep in equilibrium', one of the Oxford English Dictionary's many definitions of balance, is a desirable target for any life, but has special meaning for the life of a person with diabetes. Achieving balance-between hypo- and hyper-glycaemia; between energy intake and energy consumption; between insulin action and insulin secretion; between attention to diabetes and attention to everything else-remains challenging, but progress has been made over the last three decades, both in our understanding of how nature achieves balance and in the tools we have to try to reproduce the actions of nature in disease states. In particular, the role of the brain in controlling diabetes, from glucose sensing to decision making, has been investigated. Physiological and neuro-imaging studies are finally being translated into patient benefit, with the aim of improving, as Dr Banting put it, the provision of 'energy for the economic burdens of life'.

Original language	English
Pages (from-to)	382-392
Number of pages	11
Journal	Diabetic Medicine
Volume	31
Issue number	4
DOIs	https://doi.org/10.1111/dme.12351
Publication status	Published - Apr 2014

Keywords

DEPENDENT DIABETES-MELLITUS
COUNTERREGULATORY HORMONE RESPONSES
INTENSIFIED INSULIN-TREATMENT
BRAIN GLUCOSE-UPTAKE
HYPOGLYCEMIA UNAWARENESS
REGIONAL DIFFERENCES
CEREBRAL FUNCTION
GLYCEMIC CONTROL
PUMP THERAPY
TYPE-1

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/dme.12351

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title = "Banting Memorial Lecture 2013 A life in balance: wandering the pathways of control",

abstract = "'To keep in equilibrium', one of the Oxford English Dictionary's many definitions of balance, is a desirable target for any life, but has special meaning for the life of a person with diabetes. Achieving balance-between hypo- and hyper-glycaemia; between energy intake and energy consumption; between insulin action and insulin secretion; between attention to diabetes and attention to everything else-remains challenging, but progress has been made over the last three decades, both in our understanding of how nature achieves balance and in the tools we have to try to reproduce the actions of nature in disease states. In particular, the role of the brain in controlling diabetes, from glucose sensing to decision making, has been investigated. Physiological and neuro-imaging studies are finally being translated into patient benefit, with the aim of improving, as Dr Banting put it, the provision of 'energy for the economic burdens of life'.",

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author = "Amiel, {S. A.}",

year = "2014",

month = apr,

doi = "10.1111/dme.12351",

language = "English",

volume = "31",

pages = "382--392",

journal = "Diabetic Medicine",

issn = "0742-3071",

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T1 - Banting Memorial Lecture 2013 A life in balance

T2 - wandering the pathways of control

AU - Amiel, S. A.

PY - 2014/4

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N2 - 'To keep in equilibrium', one of the Oxford English Dictionary's many definitions of balance, is a desirable target for any life, but has special meaning for the life of a person with diabetes. Achieving balance-between hypo- and hyper-glycaemia; between energy intake and energy consumption; between insulin action and insulin secretion; between attention to diabetes and attention to everything else-remains challenging, but progress has been made over the last three decades, both in our understanding of how nature achieves balance and in the tools we have to try to reproduce the actions of nature in disease states. In particular, the role of the brain in controlling diabetes, from glucose sensing to decision making, has been investigated. Physiological and neuro-imaging studies are finally being translated into patient benefit, with the aim of improving, as Dr Banting put it, the provision of 'energy for the economic burdens of life'.

AB - 'To keep in equilibrium', one of the Oxford English Dictionary's many definitions of balance, is a desirable target for any life, but has special meaning for the life of a person with diabetes. Achieving balance-between hypo- and hyper-glycaemia; between energy intake and energy consumption; between insulin action and insulin secretion; between attention to diabetes and attention to everything else-remains challenging, but progress has been made over the last three decades, both in our understanding of how nature achieves balance and in the tools we have to try to reproduce the actions of nature in disease states. In particular, the role of the brain in controlling diabetes, from glucose sensing to decision making, has been investigated. Physiological and neuro-imaging studies are finally being translated into patient benefit, with the aim of improving, as Dr Banting put it, the provision of 'energy for the economic burdens of life'.

KW - DEPENDENT DIABETES-MELLITUS

KW - COUNTERREGULATORY HORMONE RESPONSES

KW - INTENSIFIED INSULIN-TREATMENT

KW - BRAIN GLUCOSE-UPTAKE

KW - HYPOGLYCEMIA UNAWARENESS

KW - REGIONAL DIFFERENCES

KW - CEREBRAL FUNCTION

KW - GLYCEMIC CONTROL

KW - PUMP THERAPY

KW - TYPE-1

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DO - 10.1111/dme.12351

M3 - Literature review

SN - 0742-3071

VL - 31

SP - 382

EP - 392

JO - Diabetic Medicine

JF - Diabetic Medicine

IS - 4

ER -

Banting Memorial Lecture 2013 A life in balance: wandering the pathways of control

Abstract

Keywords

UN SDGs

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