Benzodiazepines and hypnotics

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    Benzodiazepines and so-called ‘Z’ drugs are used as hypnotics. Their mode of action is to enhance the activity of central γ-aminobutyric acid. Adverse effects include anterograde amnesia and paradoxical reactions. Tolerance, dependence and withdrawal symptoms can develop, which may be minimized by intermittent dosing. Concurrent administration with central nervous system (CNS) depressants is not recommended as this produces additive CNS effects. Melatonin is also used as a hypnotic.
    Original languageEnglish
    Pages (from-to)688-690
    Number of pages3
    JournalMedicine (United Kingdom)
    Issue number12
    Publication statusPublished - Dec 2012


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