Beyond the lesion: Neuroimaging foundations for post-stroke recovery

Leeanne M. Carey; Rüdiger J. Seitz; Mark Parsons; Christopher Levi; Shawna Farquharson; Jacques Donald Tournier; Susan Palmer; Alan Connelly

doi:10.2217/fnl.13.39

Beyond the lesion: Neuroimaging foundations for post-stroke recovery

Leeanne M. Carey^*, Rüdiger J. Seitz, Mark Parsons, Christopher Levi, Shawna Farquharson, Jacques Donald Tournier, Susan Palmer, Alan Connelly

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

33 Citations (Scopus)

Abstract

A shift is emerging in the way in which we view post-stroke recovery. This shift, supported by evidence from neuroimaging studies, encourages us to look beyond the lesion and to identify viable brain networks with capacity for plasticity. In this article, the authors review current advances in neuroimaging techniques and the new insights that they have contributed. The ability to quantify salvageable tissue, evidence of changes in remote networks, changes of functional and structural connectivity, and alterations in cortical thickness are reviewed in the context of their impact on post-stroke recovery. The value of monitoring spared structural connections and functional connectivity of brain networks within and across hemispheres is highlighted.

Original language	English
Pages (from-to)	507-527
Number of pages	21
Journal	Future Neurology
Volume	8
Issue number	5
DOIs	https://doi.org/10.2217/fnl.13.39
Publication status	Published - Sept 2013

Keywords

brain networks
cortical
intrinsic functional connectivity
neuroimaging
penumbra
rehabilitation
stroke recovery
thickness
white matter tractography

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10.2217/fnl.13.39

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Beyond the lesion: Neuroimaging foundations for post-stroke recovery

Abstract

Keywords

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