TY - JOUR
T1 - Bioactive chemical constituents from Alchornea laxiflora (benth) pax and hoffman
AU - Ogundipe, O O
AU - Moody, J O
AU - Houghton, P J
AU - Odelola, H A
PY - 2001
Y1 - 2001
N2 - Quercetin-7,4'-disulphate (1) quercetin (2) quercetin-3',4'-disuIphate (3) quercetin-3,4'-diacetate (4) rutin (5) and quercetrin (6) were isolated from the ethyl acetate soluble fraction (ESM) of the crude methanolic leaf extract of Alchornea laxiflora. Purification of these compounds was carried out by column chromatography utilising sephadex LH 20 and various mixtures of water, methanol, ethanol and toluene as eluents. Structural elucidation was by UV, IR,(HNMR)-H-1 and (CNMR)-C-13 spectroscopy as well as by FAB-MS. Antimicrobial activity of isolated compounds was detected in Gram-positive, Gram-negative and fungal organisms. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.
AB - Quercetin-7,4'-disulphate (1) quercetin (2) quercetin-3',4'-disuIphate (3) quercetin-3,4'-diacetate (4) rutin (5) and quercetrin (6) were isolated from the ethyl acetate soluble fraction (ESM) of the crude methanolic leaf extract of Alchornea laxiflora. Purification of these compounds was carried out by column chromatography utilising sephadex LH 20 and various mixtures of water, methanol, ethanol and toluene as eluents. Structural elucidation was by UV, IR,(HNMR)-H-1 and (CNMR)-C-13 spectroscopy as well as by FAB-MS. Antimicrobial activity of isolated compounds was detected in Gram-positive, Gram-negative and fungal organisms. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.
UR - http://www.scopus.com/inward/record.url?scp=0035099373&partnerID=8YFLogxK
U2 - 10.1016/S0378-8741(00)00352-4
DO - 10.1016/S0378-8741(00)00352-4
M3 - Article
VL - 74
SP - 275
EP - 280
JO - Journal of Ethnopharmacology
JF - Journal of Ethnopharmacology
IS - 3
ER -