3 Citations (Scopus)
59 Downloads (Pure)

Abstract

Conjugated polymers are organic semiconductors that can be used for fluorescence microscopy of living specimens. Here, we report the encapsulation of the bright-red-emitting conjugated polymer, poly[{9,9-dihexyl-2,7-bis(1-cyanovinylene)fluorenylene}-alt-co-{2,5-bis(N,N′-diphenylamino)-1,4-phenylene}] (CN-FO-DPD), and superparamagnetic iron oxide nanoparticles (SPIONs) within poly(styrene-co-maleic anhydride) (PSMA) micelles. The resulting particles exhibited an emission peak at 657 nm, a fluorescence quantum yield of 21%, an average diameter of 65 nm, and a ζ potential of -30 mV. They are taken up by cells, and we describe their use in fluorescence microscopy of living Hela cells and zebrafish embryos and their associated cytotoxicity in HEK, HeLa, and HCE cells.

Original languageEnglish
Pages (from-to)8193–8202
Number of pages10
JournalACS Applied Polymer Materials
Volume4
Issue number11
Early online date12 Oct 2022
DOIs
Publication statusPublished - 11 Nov 2022

Fingerprint

Dive into the research topics of 'Biocompatible magnetic conjugated polymer nanoparticles for optical and lifetime imaging applications in the first biological window'. Together they form a unique fingerprint.

Cite this