Bipolar disorder, affective psychosis, and schizophrenia in pregnancy and the post-partum period

Ian Jones; Prabha S Chandra; Paola Dazzan; Louise M Howard

doi:10.1016/S0140-6736(14)61278-2

Bipolar disorder, affective psychosis, and schizophrenia in pregnancy and the post-partum period

Ian Jones, Prabha S Chandra, Paola Dazzan, Louise M Howard

Research output: Contribution to journal › Article › peer-review

427 Citations (Scopus)

Abstract

The perinatal period is associated with an increased risk of severe mental disorders. We summarise the evidence regarding the epidemiology, risk factors, and treatment of severe mental illness in relation to childbirth, focusing on bipolar disorder, affective psychosis, and schizophrenia. We discuss women with ongoing chronic conditions and those with the onset of new episodes of post-partum psychosis. Despite the importance of perinatal episodes, with suicide a leading cause of maternal death, few studies are available to guide the management of women with severe mental disorders in pregnancy and the post-partum period. However, general principles of management are discussed, including the need for an individual risk-benefit analysis for each woman.

Original language	English
Pages (from-to)	1789-1799
Number of pages	11
Journal	Lancet
Volume	384
Issue number	9956
DOIs	https://doi.org/10.1016/S0140-6736(14)61278-2
Publication status	Published - 15 Nov 2014

Keywords

Adult
Affective Disorders, Psychotic
Antipsychotic Agents
Bipolar Disorder
Female
Follow-Up Studies
Humans
Incidence
Postpartum Period
Pregnancy
Pregnancy Complications
Pregnancy Outcome
Risk Assessment
Schizophrenia
Severity of Illness Index
Treatment Outcome
Young Adult

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/S0140-6736(14)61278-2

Cite this

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abstract = "The perinatal period is associated with an increased risk of severe mental disorders. We summarise the evidence regarding the epidemiology, risk factors, and treatment of severe mental illness in relation to childbirth, focusing on bipolar disorder, affective psychosis, and schizophrenia. We discuss women with ongoing chronic conditions and those with the onset of new episodes of post-partum psychosis. Despite the importance of perinatal episodes, with suicide a leading cause of maternal death, few studies are available to guide the management of women with severe mental disorders in pregnancy and the post-partum period. However, general principles of management are discussed, including the need for an individual risk-benefit analysis for each woman.",

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AU - Jones, Ian

AU - Chandra, Prabha S

AU - Dazzan, Paola

AU - Howard, Louise M

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KW - Antipsychotic Agents

KW - Bipolar Disorder

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Incidence

KW - Postpartum Period

KW - Pregnancy

KW - Pregnancy Complications

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KW - Risk Assessment

KW - Schizophrenia

KW - Severity of Illness Index

KW - Treatment Outcome

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DO - 10.1016/S0140-6736(14)61278-2

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JO - Lancet

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ER -

Bipolar disorder, affective psychosis, and schizophrenia in pregnancy and the post-partum period

Abstract

Keywords

UN SDGs

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