Blowing Hot and Cold in ALS: The Duality of TBK1

TY - JOUR

T1 - Blowing Hot and Cold in ALS

T2 - The Duality of TBK1

AU - Mayl, Keith

AU - Sreedharan, Jemeen

PY - 2020/6/3

Y1 - 2020/6/3

N2 - Mutations in TANK-binding kinase 1 (TBK1) are linked to ALS-FTD. In this issue of Neuron, Gerbino et al. (2020) show how missense mutations in the kinase domain of TBK1 differentially affect disease onset and progression in an ALS mouse model.

AB - Mutations in TANK-binding kinase 1 (TBK1) are linked to ALS-FTD. In this issue of Neuron, Gerbino et al. (2020) show how missense mutations in the kinase domain of TBK1 differentially affect disease onset and progression in an ALS mouse model.

UR - http://www.scopus.com/inward/record.url?scp=85085297938&partnerID=8YFLogxK

U2 - 10.1016/j.neuron.2020.05.006

DO - 10.1016/j.neuron.2020.05.006

M3 - Article

C2 - 32497504

AN - SCOPUS:85085297938

SN - 0896-6273

VL - 106

SP - 705

EP - 707

JO - Neuron

JF - Neuron

IS - 5

ER -