Bone Marrow Failure in Fanconi Anemia Is Triggered by an Exacerbated p53/p21 DNA Damage Response that Impairs Hematopoietic Stem and Progenitor Cells

Raphael Ceccaldi; Kalindi Parmar; Enguerran Mouly; Marc Delord; Jung Min Kim; Marie Regairaz; Marika Pla; Nadia Vasquez; Qing-Shuo Zhang; Corinne Pondarre; Regis Peffault de Latour; Eliane Gluckman; Marina Cavazzana-Calvo; Thierry Leblanc; Jerome Larghero; Markus Grompe; Gerard Socie; Alan D. D'Andrea; Jean Soulier

doi:10.1016/j.stem.2012.05.013

Bone Marrow Failure in Fanconi Anemia Is Triggered by an Exacerbated p53/p21 DNA Damage Response that Impairs Hematopoietic Stem and Progenitor Cells

Raphael Ceccaldi, Kalindi Parmar, Enguerran Mouly, Marc Delord, Jung Min Kim, Marie Regairaz, Marika Pla, Nadia Vasquez, Qing-Shuo Zhang, Corinne Pondarre, Regis Peffault de Latour, Eliane Gluckman, Marina Cavazzana-Calvo, Thierry Leblanc, Jerome Larghero, Markus Grompe, Gerard Socie, Alan D. D'Andrea, Jean Soulier

Research output: Contribution to journal › Article › peer-review

256 Citations (Scopus)

Original language	English
Pages (from-to)	36-49
Journal	Cell Stem Cell
Volume	11
Issue number	1
DOIs	https://doi.org/10.1016/j.stem.2012.05.013
Publication status	Published - 6 Jul 2012

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10.1016/j.stem.2012.05.013

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Ceccaldi, R., Parmar, K., Mouly, E., Delord, M., Kim, J. M., Regairaz, M., Pla, M., Vasquez, N., Zhang, Q.-S., Pondarre, C., de Latour, R. P., Gluckman, E., Cavazzana-Calvo, M., Leblanc, T., Larghero, J., Grompe, M., Socie, G., D'Andrea, A. D., & Soulier, J. (2012). Bone Marrow Failure in Fanconi Anemia Is Triggered by an Exacerbated p53/p21 DNA Damage Response that Impairs Hematopoietic Stem and Progenitor Cells. Cell Stem Cell, 11(1), 36-49. https://doi.org/10.1016/j.stem.2012.05.013

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title = "Bone Marrow Failure in Fanconi Anemia Is Triggered by an Exacerbated p53/p21 DNA Damage Response that Impairs Hematopoietic Stem and Progenitor Cells",

author = "Raphael Ceccaldi and Kalindi Parmar and Enguerran Mouly and Marc Delord and Kim, {Jung Min} and Marie Regairaz and Marika Pla and Nadia Vasquez and Qing-Shuo Zhang and Corinne Pondarre and {de Latour}, {Regis Peffault} and Eliane Gluckman and Marina Cavazzana-Calvo and Thierry Leblanc and Jerome Larghero and Markus Grompe and Gerard Socie and D'Andrea, {Alan D.} and Jean Soulier",

year = "2012",

month = jul,

day = "6",

doi = "10.1016/j.stem.2012.05.013",

language = "English",

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pages = "36--49",

journal = "Cell Stem Cell",

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Ceccaldi, R, Parmar, K, Mouly, E, Delord, M, Kim, JM, Regairaz, M, Pla, M, Vasquez, N, Zhang, Q-S, Pondarre, C, de Latour, RP, Gluckman, E, Cavazzana-Calvo, M, Leblanc, T, Larghero, J, Grompe, M, Socie, G, D'Andrea, AD & Soulier, J 2012, 'Bone Marrow Failure in Fanconi Anemia Is Triggered by an Exacerbated p53/p21 DNA Damage Response that Impairs Hematopoietic Stem and Progenitor Cells', Cell Stem Cell, vol. 11, no. 1, pp. 36-49. https://doi.org/10.1016/j.stem.2012.05.013

TY - JOUR

T1 - Bone Marrow Failure in Fanconi Anemia Is Triggered by an Exacerbated p53/p21 DNA Damage Response that Impairs Hematopoietic Stem and Progenitor Cells

AU - Ceccaldi, Raphael

AU - Parmar, Kalindi

AU - Mouly, Enguerran

AU - Delord, Marc

AU - Kim, Jung Min

AU - Regairaz, Marie

AU - Pla, Marika

AU - Vasquez, Nadia

AU - Zhang, Qing-Shuo

AU - Pondarre, Corinne

AU - de Latour, Regis Peffault

AU - Gluckman, Eliane

AU - Cavazzana-Calvo, Marina

AU - Leblanc, Thierry

AU - Larghero, Jerome

AU - Grompe, Markus

AU - Socie, Gerard

AU - D'Andrea, Alan D.

AU - Soulier, Jean

PY - 2012/7/6

Y1 - 2012/7/6

U2 - 10.1016/j.stem.2012.05.013

DO - 10.1016/j.stem.2012.05.013

M3 - Article

SN - 1934-5909

VL - 11

SP - 36

EP - 49

JO - Cell Stem Cell

JF - Cell Stem Cell

IS - 1

ER -