Bone mineral densitometry in clinical practice: Differences in reference values are important

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Abstract

EDITOR,--J E Compston and colleagues emphasise the merits of assessing bone density in patients relative to that in young adults (the T score) rather than relative to that in controls matched for age (the Z score), on the basis of the recommendations of an expert panel of the World Health Organisation.1 Consensus on this issue, however, is still lacking,2 and the T score has not been widely used clinically in Britain, where comparisons with controls matched for age still dominate.

Among the limitations of bone densitometry the authors briefly note the differences in the reference data provided by the manufacturers.3 Such reference data are critical to allow accurate assessment of bone density and thus determine whether intervention is recommended. We believe that the relevance and magnitude of these differences in reference data have not been fully and widely appreciated.

Number of patients attending for bone densitometry who were defined as having osteoporosis by T scores of < -2.5 for different ranges used in Britain5 (number of centres using each reference range was identified in survey)
Original languageEnglish
Pages (from-to)1300-1301
Number of pages2
JournalBMJ, British Medical Journal (Clinical Research Ed.)
Volume311
Issue number7015
DOIs
Publication statusPublished - 11 Nov 1995

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