Brain activation during human male ejaculation revisited

Janniko R Georgiadis, A A T Simone Reinders, Ferdinand H C E Van der Graaf, Anne M J Paans, Rudie Kortekaas

Research output: Contribution to journalArticlepeer-review

43 Citations (Scopus)


In a prior [O]-H2O positron emission tomographic study we reported brain regions involved in human male ejaculation. Here, we used another, more recently acquired data set to evaluate the methodological approach of this previous study, and discovered that part of the reported activation pattern was not related to ejaculation. With a new analysis of these ejaculation data, we now demonstrate ejaculation-related activations in the deep cerebellar nuclei (dentate nucleus), anterior vermis, pons, and ventrolateral thalamus, and, most importantly, ejaculation-related deactivations throughout the prefrontal cortex. This revision offers a new and more accurate insight into the brain regions involved in human male ejaculation.
Original languageEnglish
Pages (from-to)553-7
Number of pages5
Issue number6
Publication statusPublished - 16 Apr 2007


  • Cerebellar Nuclei
  • Ejaculation
  • Humans
  • Male
  • Orgasm
  • Oxygen Radioisotopes
  • Pons
  • Positron-Emission Tomography
  • Prefrontal Cortex
  • Ventral Thalamic Nuclei


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