Brain regionalization: Of signaling centers and boundaries

TY - JOUR

T1 - Brain regionalization: Of signaling centers and boundaries

AU - Cavodeassi, Florencia

AU - Houart, Corinne

PY - 2012/3

Y1 - 2012/3

N2 - Our knowledge of the general mechanisms controlling the formation of the vertebrate central nervous system has advanced tremendously in the last decade. Here, we discuss the impact of the combined use of cell manipulation, in vivo imaging and genetics in the zebrafish on recent progress in understanding how signaling processes progressively control regionalization of the central nervous system. We highlight the unresolved issues and speculate upon the fundamental role the zebrafish will continue having in answering them. (c) 2011 Wiley Periodicals, Inc. Develop Neurobiol 72: 218233, 2012

AB - Our knowledge of the general mechanisms controlling the formation of the vertebrate central nervous system has advanced tremendously in the last decade. Here, we discuss the impact of the combined use of cell manipulation, in vivo imaging and genetics in the zebrafish on recent progress in understanding how signaling processes progressively control regionalization of the central nervous system. We highlight the unresolved issues and speculate upon the fundamental role the zebrafish will continue having in answering them. (c) 2011 Wiley Periodicals, Inc. Develop Neurobiol 72: 218233, 2012

U2 - 10.1002/dneu.20938

DO - 10.1002/dneu.20938

M3 - Literature review

SN - 1932-846X

VL - 72

SP - 218

EP - 233

JO - Developmental Neurobiology

JF - Developmental Neurobiology

IS - 3

ER -