Buccal midazolam for agitation on psychiatric intensive care wards

David Taylor, Chike Okocha, Carol Paton, Shubalade Smith, Anne Connolly

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


Midazolam is a benzodiazepine known to be effective as a treatment for status epilepticus and for rapid tranquillisation. Buccal midazolam has recently become available in the UK. We introduced it as a treatment option for rapid tranquillisation on our intensive care wards. Buccal midazolam was found to be effective and well tolerated. Target levels of sedation were achieved in nearly 70% of subjects within half an hour. Activity was evident within 15 minutes. Over-sedation occurred in only one patient at one time point. There were no cases of respiratory depression. Buccal midazolam deserves further investigation as a non-invasive treatment option in rapid tranquillisation.
Original languageEnglish
Pages (from-to)309-11
Number of pages3
JournalInternational Journal of Psychiatry in Clinical Practice
Issue number4
Publication statusPublished - 2008
EventInternational Forum on Mood and Anxiety Disorders - Vienna, Austria
Duration: 12 Nov 200814 Nov 2008


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