Building resilient and responsive research collaborations to tackle antimicrobial resistance—Lessons learnt from India, South Africa, and UK

TY - JOUR

T1 - Building resilient and responsive research collaborations to tackle antimicrobial resistance—Lessons learnt from India, South Africa, and UK

AU - Veepanattu, P.

AU - Singh, S.

AU - Mendelson, M.

AU - Nampoothiri, V.

AU - Edathadatil, F.

AU - Surendran, S.

AU - Bonaconsa, C.

AU - Mbamalu, O.

AU - Ahuja, S.

AU - Birgand, G.

AU - Tarrant, C.

AU - Sevdalis, N.

AU - Ahmad, R.

AU - Castro-Sanchez, E.

AU - Holmes, A.

AU - Charani, E.

PY - 2020/11

Y1 - 2020/11

N2 - Research, collaboration, and knowledge exchange are critical to global efforts to tackle antimicrobial resistance (AMR). Different healthcare economies are faced with different challenges in implementing effective strategies to address AMR. Building effective capacity for research to inform AMR-related strategies and policies is recognised as an important contributor to success. Interdisciplinary, intersector, as well as international collaborations are needed to span global to local efforts to tackle AMR. The development of reciprocal, long-term partnerships between collaborators in high-income and in low- and middle-income countries (LMICs) needs to be built on principles of capacity building. Using case studies spanning local and international research collaborations to codesign, implement, and evaluate strategies to tackle AMR, we have evaluated and build upon the ESSENCE criteria for capacity building in LMICs. The first case study describes the local codesign and implementation of antimicrobial stewardship (AMS) in the state of Kerala in India. The second case study describes an international research collaboration investigating AMR surgical patient pathways in India, the UK, and South Africa. We describe the steps undertaken to develop robust, agile, and flexible AMS research and implementation teams. Notably, investing in capacity building ensured that the programmes described in these case studies were sustained through the current severe acute respiratory syndrome coronavirus pandemic. Describing the strategies adopted by a local and an international collaboration to tackle AMR, we provide a model for capacity building in LMICs that can support sustainable and agile AMS programmes.

AB - Research, collaboration, and knowledge exchange are critical to global efforts to tackle antimicrobial resistance (AMR). Different healthcare economies are faced with different challenges in implementing effective strategies to address AMR. Building effective capacity for research to inform AMR-related strategies and policies is recognised as an important contributor to success. Interdisciplinary, intersector, as well as international collaborations are needed to span global to local efforts to tackle AMR. The development of reciprocal, long-term partnerships between collaborators in high-income and in low- and middle-income countries (LMICs) needs to be built on principles of capacity building. Using case studies spanning local and international research collaborations to codesign, implement, and evaluate strategies to tackle AMR, we have evaluated and build upon the ESSENCE criteria for capacity building in LMICs. The first case study describes the local codesign and implementation of antimicrobial stewardship (AMS) in the state of Kerala in India. The second case study describes an international research collaboration investigating AMR surgical patient pathways in India, the UK, and South Africa. We describe the steps undertaken to develop robust, agile, and flexible AMS research and implementation teams. Notably, investing in capacity building ensured that the programmes described in these case studies were sustained through the current severe acute respiratory syndrome coronavirus pandemic. Describing the strategies adopted by a local and an international collaboration to tackle AMR, we provide a model for capacity building in LMICs that can support sustainable and agile AMS programmes.

KW - Antimicrobial resistance

KW - Capacity building

KW - Global health

KW - Research partnerships

UR - http://www.scopus.com/inward/record.url?scp=85092321808&partnerID=8YFLogxK

U2 - 10.1016/j.ijid.2020.08.057

DO - 10.1016/j.ijid.2020.08.057

M3 - Short survey

C2 - 32860949

AN - SCOPUS:85092321808

SN - 1201-9712

VL - 100

SP - 278

EP - 282

JO - INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

JF - INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

ER -