Cardiac magnetic resonance for early atrial lesion visualization post atrial fibrillation radiofrequency catheter ablation

Marco Guglielmo, Sophie Rier, Giulia De Zan, Axel J Krafft, Michaela Schmidt, Karl P Kunze, Rene M Botnar, Claudia Prieto, Jeroen van der Heijden, Vincent Van Driel, Hemanth Ramanna, Pim van der Harst, Ivo van der Bilt

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Incomplete atrial lesions resulting in pulmonary vein-left atrium reconnection after pulmonary vein antrum isolation (PVAI), are related to atrial fibrillation (AF) recurrence. Unfortunately, during the PVAI procedure, fluoroscopy and electroanatomic mapping cannot accurately determine the location and size of the ablation lesions in the atrial wall and this can result in incomplete PVAI lesions (PVAI-L) after radiofrequency catheter ablation (RFCA). Aim: We seek to evaluate whether cardiac magnetic resonance (CMR), immediately after RFCA of AF, can identify PVAI-L by characterizing the left atrial tissue. Methods: Ten patients (63.1 ± 5.7 years old, 80% male) receiving a RFCA for paroxysmal AF underwent a CMR before (<1 week) and after (<1 h) the PVAI. Two-dimensional dark-blood T2-weighted short tau inversion recovery (DB-STIR), Three-dimensional inversion-recovery prepared long inversion time (3D-TWILITE) and three-dimensional late gadolinium enhancement (3D-LGE) images were performed to visualize PVAI-L. Results: The PVAI-L was visible in 10 patients (100%) using 3D-TWILITE and 3D-LGE. Conversely, On DB-STIR, the ablation core of the PAVI-L could not be identified because of a diffuse high signal of the atrial wall post-PVAI. Microvascular obstruction was identified in 7 (70%) patients using 3D-LGE. Conclusion: CMR can visualize PVAI-L immediately after the RFCA of AF even without the use of contrast agents. Future studies are needed to understand if the use of CMR for PVAI-L detection after RFCA can improve the results of ablation procedures.

Original languageEnglish
JournalJournal of Cardiovascular Electrophysiology
Early online date8 Dec 2023
DOIs
Publication statusE-pub ahead of print - 8 Dec 2023

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