Cardiovascular Damage in COVID-19: What We Know Two Years Later

Vincenzo Nuzzi; Eva Del Mestre; Alessia Degrassi; Daniel I. Bromage; Paolo Manca; Susan Piper; Jessica Artico; Piero Gentile; Paul A. Scott; Mario Chiatto; Marco Merlo; Nilesh Pareek; Mauro Giacca; Gianfranco Sinagra; Theresa A. McDonagh; Antonio Cannata

doi:10.1007/s11886-022-01730-4

Cardiovascular Damage in COVID-19: What We Know Two Years Later

Vincenzo Nuzzi, Eva Del Mestre, Alessia Degrassi, Daniel I. Bromage, Paolo Manca, Susan Piper, Jessica Artico, Piero Gentile, Paul A. Scott, Mario Chiatto, Marco Merlo, Nilesh Pareek, Mauro Giacca, Gianfranco Sinagra, Theresa A. McDonagh, Antonio Cannata^*

^*Corresponding author for this work

Cardiovascular Sciences

Research output: Contribution to journal › Review article › peer-review

5 Citations (Scopus)

Abstract

Purpose of the Review: The Coronavirus disease 2019 (COVID-19) pandemic has profoundly influenced cardiological clinical and basic research in the past two years. In the present review, we summarize the current knowledge on myocardial involvement in COVID-19, providing an overview on the incidence, the pathogenetic mechanisms, and the clinical implications of cardiac injury in this setting. Recent Findings: The possibility of heart involvement in patients with COVID-19 has received great attention since the beginning of the pandemic. After more than two years, several steps have been taken in understanding the mechanisms and the incidence of cardiac injury during COVID-19 infection. Similarly, studies globally have clarified the implications of co-existing heart disease and COVID-19. Summary: Severe COVID-19 infection may be complicated by myocardial injury. To date, a direct damage from the virus has not been demonstrated. The presence of myocardial injury should be systematically assessed for a prognostication purpose and for possible therapeutic implications.

Original language	English
Pages (from-to)	1085-1091
Number of pages	7
Journal	Current cardiology reports
Volume	24
Issue number	9
DOIs	https://doi.org/10.1007/s11886-022-01730-4
Publication status	Published - Sept 2022

Keywords

Acute cardiac damage
Biomarkers
Cardiovascular injury
COVID-19

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s11886-022-01730-4

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Nuzzi, V., Del Mestre, E., Degrassi, A., Bromage, D. I., Manca, P., Piper, S., Artico, J., Gentile, P., Scott, P. A., Chiatto, M., Merlo, M., Pareek, N., Giacca, M., Sinagra, G., McDonagh, T. A., & Cannata, A. (2022). Cardiovascular Damage in COVID-19: What We Know Two Years Later. Current cardiology reports, 24(9), 1085-1091. https://doi.org/10.1007/s11886-022-01730-4

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abstract = "Purpose of the Review: The Coronavirus disease 2019 (COVID-19) pandemic has profoundly influenced cardiological clinical and basic research in the past two years. In the present review, we summarize the current knowledge on myocardial involvement in COVID-19, providing an overview on the incidence, the pathogenetic mechanisms, and the clinical implications of cardiac injury in this setting. Recent Findings: The possibility of heart involvement in patients with COVID-19 has received great attention since the beginning of the pandemic. After more than two years, several steps have been taken in understanding the mechanisms and the incidence of cardiac injury during COVID-19 infection. Similarly, studies globally have clarified the implications of co-existing heart disease and COVID-19. Summary: Severe COVID-19 infection may be complicated by myocardial injury. To date, a direct damage from the virus has not been demonstrated. The presence of myocardial injury should be systematically assessed for a prognostication purpose and for possible therapeutic implications.",

keywords = "Acute cardiac damage, Biomarkers, Cardiovascular injury, COVID-19",

author = "Vincenzo Nuzzi and {Del Mestre}, Eva and Alessia Degrassi and Bromage, {Daniel I.} and Paolo Manca and Susan Piper and Jessica Artico and Piero Gentile and Scott, {Paul A.} and Mario Chiatto and Marco Merlo and Nilesh Pareek and Mauro Giacca and Gianfranco Sinagra and McDonagh, {Theresa A.} and Antonio Cannata",

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year = "2022",

month = sep,

doi = "10.1007/s11886-022-01730-4",

language = "English",

volume = "24",

pages = "1085--1091",

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T1 - Cardiovascular Damage in COVID-19

T2 - What We Know Two Years Later

AU - Nuzzi, Vincenzo

AU - Del Mestre, Eva

AU - Degrassi, Alessia

AU - Bromage, Daniel I.

AU - Manca, Paolo

AU - Piper, Susan

AU - Artico, Jessica

AU - Gentile, Piero

AU - Scott, Paul A.

AU - Chiatto, Mario

AU - Merlo, Marco

AU - Pareek, Nilesh

AU - Giacca, Mauro

AU - Sinagra, Gianfranco

AU - McDonagh, Theresa A.

AU - Cannata, Antonio

PY - 2022/9

Y1 - 2022/9

N2 - Purpose of the Review: The Coronavirus disease 2019 (COVID-19) pandemic has profoundly influenced cardiological clinical and basic research in the past two years. In the present review, we summarize the current knowledge on myocardial involvement in COVID-19, providing an overview on the incidence, the pathogenetic mechanisms, and the clinical implications of cardiac injury in this setting. Recent Findings: The possibility of heart involvement in patients with COVID-19 has received great attention since the beginning of the pandemic. After more than two years, several steps have been taken in understanding the mechanisms and the incidence of cardiac injury during COVID-19 infection. Similarly, studies globally have clarified the implications of co-existing heart disease and COVID-19. Summary: Severe COVID-19 infection may be complicated by myocardial injury. To date, a direct damage from the virus has not been demonstrated. The presence of myocardial injury should be systematically assessed for a prognostication purpose and for possible therapeutic implications.

AB - Purpose of the Review: The Coronavirus disease 2019 (COVID-19) pandemic has profoundly influenced cardiological clinical and basic research in the past two years. In the present review, we summarize the current knowledge on myocardial involvement in COVID-19, providing an overview on the incidence, the pathogenetic mechanisms, and the clinical implications of cardiac injury in this setting. Recent Findings: The possibility of heart involvement in patients with COVID-19 has received great attention since the beginning of the pandemic. After more than two years, several steps have been taken in understanding the mechanisms and the incidence of cardiac injury during COVID-19 infection. Similarly, studies globally have clarified the implications of co-existing heart disease and COVID-19. Summary: Severe COVID-19 infection may be complicated by myocardial injury. To date, a direct damage from the virus has not been demonstrated. The presence of myocardial injury should be systematically assessed for a prognostication purpose and for possible therapeutic implications.

KW - Acute cardiac damage

KW - Biomarkers

KW - Cardiovascular injury

KW - COVID-19

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DO - 10.1007/s11886-022-01730-4

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AN - SCOPUS:85132827466

SN - 1523-3782

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EP - 1091

JO - Current cardiology reports

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ER -

Cardiovascular Damage in COVID-19: What We Know Two Years Later

Abstract

Keywords

UN SDGs

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