Cathepsin B Mediated Lysosomal Degradation in Macrophages Controls the Pharmacokinetics of the Therapeutic Protein Asparaginase

Laurens T. Van Der Meer, Samantha Y. A. Terry, Dorette van Ingen Schenau, Kiki Andree, Gerben M. Franssen, Debbie Roeleveld, Bart Metselaar, Thomas Reinheckel, Peter M. Hoogerbrugge, Otto C. Boerman, Frank N. van Leeuwen

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Immunology and Microbiology

Pharmacology, Toxicology and Pharmaceutical Science