Cell-free plasma DNA as a prognostic marker in intensive treatment unit patients

D S B Hoon; B Taback; S Burns; K Sherwood; O Boyd; R Swaminathan

Cell-free plasma DNA as a prognostic marker in intensive treatment unit patients

D S B Hoon (Editor), B Taback, S Burns, K Sherwood, O Boyd, R Swaminathan

King's College London

Research output: Chapter in Book/Report/Conference proceeding › Conference paper

58 Citations (Scopus)

Abstract

Recent evidence suggests that cell-free plasma DNA has potential use as a prognostic marker in many clinical settings. The aim of the present study was to evaluate the prognostic role of cell-free plasma DNA in the prediction of clinical outcome in intensive treatment unit (ITU) patients. Cell-free plasma DNA was measured by real-time polymerase chain reaction assay for the beta-globin gene and SOFA score, APACHE II score, CRP concentrations, and clinical outcome (duration of stay, ventilation time, and mortality) were noted in 94 patients on admission to the ITU. The median plasma DNA concentration in ITU patients was 5493 GE/mL and this was significantly (P

Original language	English
Title of host publication	Ann.NY Acad.Sci.
Place of Publication	NEW YORK
Publisher	New York Acad Sciences
Pages	232 - 238
Number of pages	7
ISBN (Print)	1-57331-551-6
Publication status	Published - 2004
Event	3rd International Symposium on Circulating Nucleic Acids in Plasma/Serum (CNAPS III) and Serum Proteomics - Santa Monica, CA Duration: 1 Jan 2004 → …

Publication series

Name	ANNALS OF THE NEW YORK ACADEMY OF SCIENCES

Conference

Conference	3rd International Symposium on Circulating Nucleic Acids in Plasma/Serum (CNAPS III) and Serum Proteomics
City	Santa Monica, CA
Period	1/01/2004 → …

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This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "Cell-free plasma DNA as a prognostic marker in intensive treatment unit patients",

abstract = "Recent evidence suggests that cell-free plasma DNA has potential use as a prognostic marker in many clinical settings. The aim of the present study was to evaluate the prognostic role of cell-free plasma DNA in the prediction of clinical outcome in intensive treatment unit (ITU) patients. Cell-free plasma DNA was measured by real-time polymerase chain reaction assay for the beta-globin gene and SOFA score, APACHE II score, CRP concentrations, and clinical outcome (duration of stay, ventilation time, and mortality) were noted in 94 patients on admission to the ITU. The median plasma DNA concentration in ITU patients was 5493 GE/mL and this was significantly (P ",

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year = "2004",

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series = "ANNALS OF THE NEW YORK ACADEMY OF SCIENCES",

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}

Hoon, DSB (ed.), Taback, B, Burns, S, Sherwood, K, Boyd, O & Swaminathan, R 2004, Cell-free plasma DNA as a prognostic marker in intensive treatment unit patients. in Ann.NY Acad.Sci.. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, New York Acad Sciences, NEW YORK, pp. 232 - 238, 3rd International Symposium on Circulating Nucleic Acids in Plasma/Serum (CNAPS III) and Serum Proteomics, Santa Monica, CA, 1/01/2004.

TY - CHAP

T1 - Cell-free plasma DNA as a prognostic marker in intensive treatment unit patients

AU - Taback, B

AU - Burns, S

AU - Sherwood, K

AU - Boyd, O

AU - Swaminathan, R

A2 - Hoon, D S B

PY - 2004

Y1 - 2004

N2 - Recent evidence suggests that cell-free plasma DNA has potential use as a prognostic marker in many clinical settings. The aim of the present study was to evaluate the prognostic role of cell-free plasma DNA in the prediction of clinical outcome in intensive treatment unit (ITU) patients. Cell-free plasma DNA was measured by real-time polymerase chain reaction assay for the beta-globin gene and SOFA score, APACHE II score, CRP concentrations, and clinical outcome (duration of stay, ventilation time, and mortality) were noted in 94 patients on admission to the ITU. The median plasma DNA concentration in ITU patients was 5493 GE/mL and this was significantly (P

AB - Recent evidence suggests that cell-free plasma DNA has potential use as a prognostic marker in many clinical settings. The aim of the present study was to evaluate the prognostic role of cell-free plasma DNA in the prediction of clinical outcome in intensive treatment unit (ITU) patients. Cell-free plasma DNA was measured by real-time polymerase chain reaction assay for the beta-globin gene and SOFA score, APACHE II score, CRP concentrations, and clinical outcome (duration of stay, ventilation time, and mortality) were noted in 94 patients on admission to the ITU. The median plasma DNA concentration in ITU patients was 5493 GE/mL and this was significantly (P

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M3 - Conference paper

SN - 1-57331-551-6

T3 - ANNALS OF THE NEW YORK ACADEMY OF SCIENCES

SP - 232

EP - 238

BT - Ann.NY Acad.Sci.

PB - New York Acad Sciences

CY - NEW YORK

T2 - 3rd International Symposium on Circulating Nucleic Acids in Plasma/Serum (CNAPS III) and Serum Proteomics

Y2 - 1 January 2004

ER -

Cell-free plasma DNA as a prognostic marker in intensive treatment unit patients

Abstract

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