Chandelier cells shine a light on the formation of GABAergic synapses

Benjamin Compans, Juan Burrone*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

Uncovering the wiring rules employed by neurons during development represents a formidable challenge with important repercussions for neurodevelopmental disorders. Chandelier cells (ChCs) are a singular GABAergic interneuron type, with a unique morphology, that have recently begun to shed light on the rules that drive the formation and plasticity of inhibitory synapses. This review will focus on the wealth of recent data charting the emergence of synapses formed by ChCs onto pyramidal cells, from the molecules involved to the plasticity of these connections during development.

Original languageEnglish
Article number102697
JournalCURRENT OPINION IN NEUROBIOLOGY
Volume80
DOIs
Publication statusPublished - Jun 2023

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