@inbook{257887b1377343adb8bebe06f064c351,
title = "CHAPTER 6: Colchicine-, Vinblastine-, Taxol- A nd Eribulin-based Payloads for Antibody-Drug Conjugates (ADCs)",
abstract = "Significant advances in cancer therapeutics have been made in the past few decades, and novel anticancer agents are now being discovered and developed at a rapid pace compared with the last century.1 Inhibition of cellular microtubules still represents one of the most important mechanisms of action of the present generation of cytotoxic agents.2 Microtubule inhibitors work by disrupting the microtubules that facilitate the separation of chromosomes during cell division (Figure 6.1).",
author = "Arpita Velani and Syafiq Kay and Albone, {Earl F.} and Thurston, {David E.}",
year = "2019",
month = jan,
day = "1",
doi = "10.1039/9781788012898-00117",
language = "English",
series = "RSC Drug Discovery Series",
publisher = "Royal Society of Chemistry",
number = "71",
pages = "117--136",
editor = "Thurston, {David E.} and Jackson, {Paul J. M.}",
booktitle = "Therapies for Retinal Degeneration",
address = "United Kingdom",
edition = "71",
}
