Characterisation of heart rate changes and their correlation with EEG during neonatal seizures

O M Doyle, B R Greene, W Marnane, G Lightbody, G B Boylan

Research output: Chapter in Book/Report/Conference proceedingConference paper

7 Citations (Scopus)


The effect of seizures on instantaneous HR (iHR) in 12 neonates is investigated here. HR can be readily extracted from the ECG and can be employed as an additional signal in seizure detection algorithms. The change in instantaneous HR and its correlation with the change in RMS EEG amplitude were examined. Two methods were employed to classify significant iHR changes. Significant correlation (p 0.05) during seizure was observed in 100% of patients (83.33% of seizures). Overall, significant iHR changes (classified by either method) were found in 83% of patients (50% of seizures). It was found that a markedly higher iHR was observed in patients whose seizures were not classified as having significant iHR changes.
Original languageEnglish
Title of host publicationEMBC 2008 : Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society :
Subtitle of host publication"personalized healthcare through technology" : August 20-24, 2008, Vancouver, British Columbia, Canada
Place of PublicationPiscataway, N.J.
Number of pages4
ISBN (Electronic)978-1-4244-1815-2
ISBN (Print)978-1-4244-1814-5
Publication statusPublished - 2008

Publication series

ISSN (Print)1557-170X


  • Sensitivity and Specificity
  • Reproducibility of Results
  • Humans
  • Diagnosis, Computer-Assisted
  • Electroencephalography
  • Seizures
  • Infant, Newborn
  • Heart Rate
  • Electrocardiography
  • Statistics as Topic
  • Neonatal Screening
  • Female
  • Male


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