Cholecystectomy in English Children: Evidence of an Epidemic (1997-2012)

Abigail Kate Khoo; Rufus Cartwright; Simon Berry; Mark Davenport

doi:10.1016/j.jpedsurg.2013.11.053

Cholecystectomy in English Children: Evidence of an Epidemic (1997-2012)

Abigail Kate Khoo, Rufus Cartwright, Simon Berry, Mark Davenport^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

39 Citations (Scopus)

Abstract

Background/Purpose: The purpose of this study was to calculate the incidence of cholecystectomy among children aged

Methods: A nationwide retrospective cohort study using the Hospital Episode Statistics Database for episodes of cholecystectomy in children aged

Results: 2808 paediatric cholecystectomies were identified. The incidence of cholecystectomy increased from 0.78/100,000 to 2.7/100,000 (P <0.0001). Sex-specific incidences increased from 1.1 to 4.36/100,000 (P <0.0001) among girls and from 0.48 to 1.13/100,000 (P <0.0001) among boys. There were significant changes in case mix, with an increasing proportion of female cases (69% to 79%, P = 0.02), an increase in cases of white ethnicity (48% to 77%, P <0.0001), but only a modest increase in those with a diagnosis of sickle cell anaemia (4% to 6%, P = 0.02), and no significant increase in other haemolytic anaemias.

Conclusions: There has been a three-fold increase in the incidence of paediatric cholecystectomy in England since 1997, with a particular rise among white females. Although data on BMI were not available, the observed effect may be a consequence of increasing levels of teenage obesity.

Original language	English
Pages (from-to)	284-288
Number of pages	5
Journal	Journal of Pediatric Surgery
Volume	49
Issue number	2
DOIs	https://doi.org/10.1016/j.jpedsurg.2013.11.053
Publication status	Published - Feb 2014

Keywords

Gallstones
Cholecystectomy
Children
Obesity
Hospital Episode Statistics
SICKLE-CELL-DISEASE
LAPAROSCOPIC CHOLECYSTECTOMY
BILIARY DYSKINESIA
PEDIATRIC CHOLECYSTECTOMY
GALLBLADDER-DISEASE
GALLSTONE DISEASE
RISK-FACTORS
OUTCOMES
POPULATION
OBESITY

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jpedsurg.2013.11.053

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title = "Cholecystectomy in English Children: Evidence of an Epidemic (1997-2012)",

abstract = "Background/Purpose: The purpose of this study was to calculate the incidence of cholecystectomy among children aged Methods: A nationwide retrospective cohort study using the Hospital Episode Statistics Database for episodes of cholecystectomy in children aged Results: 2808 paediatric cholecystectomies were identified. The incidence of cholecystectomy increased from 0.78/100,000 to 2.7/100,000 (P <0.0001). Sex-specific incidences increased from 1.1 to 4.36/100,000 (P <0.0001) among girls and from 0.48 to 1.13/100,000 (P <0.0001) among boys. There were significant changes in case mix, with an increasing proportion of female cases (69% to 79%, P = 0.02), an increase in cases of white ethnicity (48% to 77%, P <0.0001), but only a modest increase in those with a diagnosis of sickle cell anaemia (4% to 6%, P = 0.02), and no significant increase in other haemolytic anaemias. Conclusions: There has been a three-fold increase in the incidence of paediatric cholecystectomy in England since 1997, with a particular rise among white females. Although data on BMI were not available, the observed effect may be a consequence of increasing levels of teenage obesity.",

keywords = "Gallstones, Cholecystectomy, Children, Obesity, Hospital Episode Statistics, SICKLE-CELL-DISEASE, LAPAROSCOPIC CHOLECYSTECTOMY, BILIARY DYSKINESIA, PEDIATRIC CHOLECYSTECTOMY, GALLBLADDER-DISEASE, GALLSTONE DISEASE, RISK-FACTORS, OUTCOMES, POPULATION, OBESITY",

author = "Khoo, {Abigail Kate} and Rufus Cartwright and Simon Berry and Mark Davenport",

year = "2014",

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doi = "10.1016/j.jpedsurg.2013.11.053",

language = "English",

volume = "49",

pages = "284--288",

journal = "Journal of Pediatric Surgery",

issn = "0022-3468",

publisher = "W.B. Saunders Ltd",

number = "2",

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T1 - Cholecystectomy in English Children: Evidence of an Epidemic (1997-2012)

AU - Khoo, Abigail Kate

AU - Cartwright, Rufus

AU - Berry, Simon

AU - Davenport, Mark

PY - 2014/2

Y1 - 2014/2

N2 - Background/Purpose: The purpose of this study was to calculate the incidence of cholecystectomy among children aged Methods: A nationwide retrospective cohort study using the Hospital Episode Statistics Database for episodes of cholecystectomy in children aged Results: 2808 paediatric cholecystectomies were identified. The incidence of cholecystectomy increased from 0.78/100,000 to 2.7/100,000 (P <0.0001). Sex-specific incidences increased from 1.1 to 4.36/100,000 (P <0.0001) among girls and from 0.48 to 1.13/100,000 (P <0.0001) among boys. There were significant changes in case mix, with an increasing proportion of female cases (69% to 79%, P = 0.02), an increase in cases of white ethnicity (48% to 77%, P <0.0001), but only a modest increase in those with a diagnosis of sickle cell anaemia (4% to 6%, P = 0.02), and no significant increase in other haemolytic anaemias. Conclusions: There has been a three-fold increase in the incidence of paediatric cholecystectomy in England since 1997, with a particular rise among white females. Although data on BMI were not available, the observed effect may be a consequence of increasing levels of teenage obesity.

AB - Background/Purpose: The purpose of this study was to calculate the incidence of cholecystectomy among children aged Methods: A nationwide retrospective cohort study using the Hospital Episode Statistics Database for episodes of cholecystectomy in children aged Results: 2808 paediatric cholecystectomies were identified. The incidence of cholecystectomy increased from 0.78/100,000 to 2.7/100,000 (P <0.0001). Sex-specific incidences increased from 1.1 to 4.36/100,000 (P <0.0001) among girls and from 0.48 to 1.13/100,000 (P <0.0001) among boys. There were significant changes in case mix, with an increasing proportion of female cases (69% to 79%, P = 0.02), an increase in cases of white ethnicity (48% to 77%, P <0.0001), but only a modest increase in those with a diagnosis of sickle cell anaemia (4% to 6%, P = 0.02), and no significant increase in other haemolytic anaemias. Conclusions: There has been a three-fold increase in the incidence of paediatric cholecystectomy in England since 1997, with a particular rise among white females. Although data on BMI were not available, the observed effect may be a consequence of increasing levels of teenage obesity.

KW - Gallstones

KW - Cholecystectomy

KW - Children

KW - Obesity

KW - Hospital Episode Statistics

KW - SICKLE-CELL-DISEASE

KW - LAPAROSCOPIC CHOLECYSTECTOMY

KW - BILIARY DYSKINESIA

KW - PEDIATRIC CHOLECYSTECTOMY

KW - GALLBLADDER-DISEASE

KW - GALLSTONE DISEASE

KW - RISK-FACTORS

KW - OUTCOMES

KW - POPULATION

KW - OBESITY

U2 - 10.1016/j.jpedsurg.2013.11.053

DO - 10.1016/j.jpedsurg.2013.11.053

M3 - Article

SN - 0022-3468

VL - 49

SP - 284

EP - 288

JO - Journal of Pediatric Surgery

JF - Journal of Pediatric Surgery

IS - 2

ER -

Cholecystectomy in English Children: Evidence of an Epidemic (1997-2012)

Abstract

Keywords

UN SDGs

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