Clinical Application of Dynamic Contrast Enhanced Perfusion Imaging by Cardiovascular Magnetic Resonance

Russell Franks, Sven Plein, Amedeo Chiribiri*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

5 Citations (Scopus)


Functionally significant coronary artery disease impairs myocardial blood flow and can be detected non-invasively by myocardial perfusion imaging. While multiple myocardial perfusion imaging modalities exist, the high spatial and temporal resolution of cardiovascular magnetic resonance (CMR), combined with its freedom from ionising radiation make it an attractive option. Dynamic contrast enhanced CMR perfusion imaging has become a well-validated non-invasive tool for the assessment and risk stratification of patients with coronary artery disease and is recommended by international guidelines. This article presents an overview of CMR perfusion imaging and its clinical application, with a focus on chronic coronary syndromes, highlighting its strengths and challenges, and discusses recent advances, including the emerging role of quantitative perfusion analysis.

Original languageEnglish
Article number768563
JournalFrontiers in Cardiovascular Medicine
Publication statusPublished - 2021


  • cardiovascular magnetic resonance (CMR)
  • coronary artery disease
  • dynamic contrast enhance magnetic resonance
  • first-pass perfusion MRI
  • myocardial perfusion imaging (MPI)
  • quantitative perfusion

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