TY - JOUR
T1 - Clinical Application of Dynamic Contrast Enhanced Perfusion Imaging by Cardiovascular Magnetic Resonance
AU - Franks, Russell
AU - Plein, Sven
AU - Chiribiri, Amedeo
N1 - Funding Information:
The authors would like to acknowledge Drs. Xenios Milidonis and Cian Scannell of King's College London, School of Biomedical Engineering and Imaging Sciences for providing the perfusion maps displayed in Figures 4, 5, respectively.
Funding Information:
The authors acknowledge financial support from: The British Heart Foundation [PG/18/71/34009 and TG/18/2/33768]; The Department of Health via the National Institute for Health Research (NIHR) comprehensive Biomedical Research Centre award to Guy's & St Thomas' NHS Foundation Trust in partnership with King's College London and King's College Hospital NHS Foundation Trust; The NIHR Cardiovascular MedTech Co-operative; Wellcome/EPSRC Centre for Medical Engineering [WT 203148/Z/16/Z].
Publisher Copyright:
Copyright © 2021 Franks, Plein and Chiribiri.
PY - 2021
Y1 - 2021
N2 - Functionally significant coronary artery disease impairs myocardial blood flow and can be detected non-invasively by myocardial perfusion imaging. While multiple myocardial perfusion imaging modalities exist, the high spatial and temporal resolution of cardiovascular magnetic resonance (CMR), combined with its freedom from ionising radiation make it an attractive option. Dynamic contrast enhanced CMR perfusion imaging has become a well-validated non-invasive tool for the assessment and risk stratification of patients with coronary artery disease and is recommended by international guidelines. This article presents an overview of CMR perfusion imaging and its clinical application, with a focus on chronic coronary syndromes, highlighting its strengths and challenges, and discusses recent advances, including the emerging role of quantitative perfusion analysis.
AB - Functionally significant coronary artery disease impairs myocardial blood flow and can be detected non-invasively by myocardial perfusion imaging. While multiple myocardial perfusion imaging modalities exist, the high spatial and temporal resolution of cardiovascular magnetic resonance (CMR), combined with its freedom from ionising radiation make it an attractive option. Dynamic contrast enhanced CMR perfusion imaging has become a well-validated non-invasive tool for the assessment and risk stratification of patients with coronary artery disease and is recommended by international guidelines. This article presents an overview of CMR perfusion imaging and its clinical application, with a focus on chronic coronary syndromes, highlighting its strengths and challenges, and discusses recent advances, including the emerging role of quantitative perfusion analysis.
KW - cardiovascular magnetic resonance (CMR)
KW - coronary artery disease
KW - dynamic contrast enhance magnetic resonance
KW - first-pass perfusion MRI
KW - myocardial perfusion imaging (MPI)
KW - quantitative perfusion
UR - http://www.scopus.com/inward/record.url?scp=85125871954&partnerID=8YFLogxK
U2 - 10.3389/fcvm.2021.768563
DO - 10.3389/fcvm.2021.768563
M3 - Review article
AN - SCOPUS:85125871954
SN - 2297-055X
VL - 8
JO - Frontiers in Cardiovascular Medicine
JF - Frontiers in Cardiovascular Medicine
M1 - 768563
ER -