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Clinical evaluation of autistic symptoms in women with anorexia nervosa

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Clinical evaluation of autistic symptoms in women with anorexia nervosa. / Westwood, Heather; Mandy, William; Tchanturia, Kate.

In: Molecular Autism, Vol. 8, No. 12, 16.03.2017.

Research output: Contribution to journalArticle

Harvard

Westwood, H, Mandy, W & Tchanturia, K 2017, 'Clinical evaluation of autistic symptoms in women with anorexia nervosa', Molecular Autism, vol. 8, no. 12. https://doi.org/10.1186/s13229-017-0128-x

APA

Westwood, H., Mandy, W., & Tchanturia, K. (2017). Clinical evaluation of autistic symptoms in women with anorexia nervosa. Molecular Autism, 8(12). https://doi.org/10.1186/s13229-017-0128-x

Vancouver

Westwood H, Mandy W, Tchanturia K. Clinical evaluation of autistic symptoms in women with anorexia nervosa. Molecular Autism. 2017 Mar 16;8(12). https://doi.org/10.1186/s13229-017-0128-x

Author

Westwood, Heather ; Mandy, William ; Tchanturia, Kate. / Clinical evaluation of autistic symptoms in women with anorexia nervosa. In: Molecular Autism. 2017 ; Vol. 8, No. 12.

Bibtex Download

@article{3bae5c1a5f9a4f41b6253f454415c8e7,
title = "Clinical evaluation of autistic symptoms in women with anorexia nervosa",
abstract = "BackgroundDespite a suggested link between anorexia nervosa (AN) and autism spectrum disorder (ASD), previous studies have used self-report or diagnostic criteria to assess for ASD in AN populations, rather than direct observation of symptom characteristic of ASD. The aim of this study was to use a standardised, clinical assessment of ASD, the Autism Diagnostic Observation Schedule, 2nd Edition (ADOS-2), to investigate the presence of autistic symptoms in a cross-sectional sample of women with AN.MethodsSixty women were recruited from inpatient or day-patient specialist eating disorder services. Each participant underwent the ADOS-2 assessment and completed a set of self-report questionnaires assessing eating disorder pathology and other psychiatric symptoms. IQ was also assessed.ResultsFourteen women (23.3{\%}) scored above clinical cutoff for ASD on the ADOS-2. Only eight of these women displayed repetitive or restrictive behaviours, while all 14 had difficulties with social affect. Elevated ASD symptoms were associated with increased alexithymia and obsessive-compulsive symptoms, but not specific eating disorder pathology.ConclusionsASD symptoms are over-represented in women with severe AN and appear to be associated with other psychiatric symptoms, which warrant further investigation and consideration in treatment.",
keywords = "Anorexia Nervosa, female ASD, ADOS -2, COMORBIDITY",
author = "Heather Westwood and William Mandy and Kate Tchanturia",
year = "2017",
month = "3",
day = "16",
doi = "10.1186/s13229-017-0128-x",
language = "English",
volume = "8",
journal = "Molecular Autism",
issn = "2040-2392",
publisher = "BioMed Central",
number = "12",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - Clinical evaluation of autistic symptoms in women with anorexia nervosa

AU - Westwood, Heather

AU - Mandy, William

AU - Tchanturia, Kate

PY - 2017/3/16

Y1 - 2017/3/16

N2 - BackgroundDespite a suggested link between anorexia nervosa (AN) and autism spectrum disorder (ASD), previous studies have used self-report or diagnostic criteria to assess for ASD in AN populations, rather than direct observation of symptom characteristic of ASD. The aim of this study was to use a standardised, clinical assessment of ASD, the Autism Diagnostic Observation Schedule, 2nd Edition (ADOS-2), to investigate the presence of autistic symptoms in a cross-sectional sample of women with AN.MethodsSixty women were recruited from inpatient or day-patient specialist eating disorder services. Each participant underwent the ADOS-2 assessment and completed a set of self-report questionnaires assessing eating disorder pathology and other psychiatric symptoms. IQ was also assessed.ResultsFourteen women (23.3%) scored above clinical cutoff for ASD on the ADOS-2. Only eight of these women displayed repetitive or restrictive behaviours, while all 14 had difficulties with social affect. Elevated ASD symptoms were associated with increased alexithymia and obsessive-compulsive symptoms, but not specific eating disorder pathology.ConclusionsASD symptoms are over-represented in women with severe AN and appear to be associated with other psychiatric symptoms, which warrant further investigation and consideration in treatment.

AB - BackgroundDespite a suggested link between anorexia nervosa (AN) and autism spectrum disorder (ASD), previous studies have used self-report or diagnostic criteria to assess for ASD in AN populations, rather than direct observation of symptom characteristic of ASD. The aim of this study was to use a standardised, clinical assessment of ASD, the Autism Diagnostic Observation Schedule, 2nd Edition (ADOS-2), to investigate the presence of autistic symptoms in a cross-sectional sample of women with AN.MethodsSixty women were recruited from inpatient or day-patient specialist eating disorder services. Each participant underwent the ADOS-2 assessment and completed a set of self-report questionnaires assessing eating disorder pathology and other psychiatric symptoms. IQ was also assessed.ResultsFourteen women (23.3%) scored above clinical cutoff for ASD on the ADOS-2. Only eight of these women displayed repetitive or restrictive behaviours, while all 14 had difficulties with social affect. Elevated ASD symptoms were associated with increased alexithymia and obsessive-compulsive symptoms, but not specific eating disorder pathology.ConclusionsASD symptoms are over-represented in women with severe AN and appear to be associated with other psychiatric symptoms, which warrant further investigation and consideration in treatment.

KW - Anorexia Nervosa

KW - female ASD

KW - ADOS -2

KW - COMORBIDITY

U2 - 10.1186/s13229-017-0128-x

DO - 10.1186/s13229-017-0128-x

M3 - Article

C2 - 28331571

VL - 8

JO - Molecular Autism

JF - Molecular Autism

SN - 2040-2392

IS - 12

ER -

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