Clinical guidelines for the management of acute viral infections in patients with systemic lupus erythematosus

M. Ramos-Casals; M. J. Cuadrado; P. Alba; G. Sanna; P. Brito-Zeron; L. Bertolaccini; A. Babini; A. Moreno; D. D'Cruz; M. A. Khamashta

Clinical guidelines for the management of acute viral infections in patients with systemic lupus erythematosus

M. Ramos-Casals, M. J. Cuadrado, P. Alba, G. Sanna, P. Brito-Zeron, L. Bertolaccini, A. Babini, A. Moreno, D. D'Cruz, M. A. Khamashta

Women & Children's Health

Research output: Contribution to journal › Literature review › peer-review

7 Citations (Scopus)

Abstract

In recent decades, many research groups have focused on the role of viral infections in the etiopathogenesis of systemic lupus erythematosus (SLE), the so-called "viral hypothesis". The main candidates are herpes viruses such as Epstein-Barr virus (EBV) and cytomegalovirus (CMV), which have a high seroprevalence in the general population. However, a viral causal agent of SLE has not yet been discovered, although many interesting clinical findings on the complex interactions between viruses and SLE have been made. This review analyzes 88 cases of acute viral infections in adult patients with SLE and identifies situations in which viral infections influenced the diagnosis, prognosis or treatment of SLE. We also propose clinical guidelines for the management of these infections in patients with SLE.

Original language	English
Pages (from-to)	437 - 446
Number of pages	10
Journal	Minerva Medica
Volume	100
Issue number	6
Publication status	Published - Dec 2009

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title = "Clinical guidelines for the management of acute viral infections in patients with systemic lupus erythematosus",

abstract = "In recent decades, many research groups have focused on the role of viral infections in the etiopathogenesis of systemic lupus erythematosus (SLE), the so-called {"}viral hypothesis{"}. The main candidates are herpes viruses such as Epstein-Barr virus (EBV) and cytomegalovirus (CMV), which have a high seroprevalence in the general population. However, a viral causal agent of SLE has not yet been discovered, although many interesting clinical findings on the complex interactions between viruses and SLE have been made. This review analyzes 88 cases of acute viral infections in adult patients with SLE and identifies situations in which viral infections influenced the diagnosis, prognosis or treatment of SLE. We also propose clinical guidelines for the management of these infections in patients with SLE.",

author = "M. Ramos-Casals and Cuadrado, {M. J.} and P. Alba and G. Sanna and P. Brito-Zeron and L. Bertolaccini and A. Babini and A. Moreno and D. D'Cruz and Khamashta, {M. A.}",

year = "2009",

month = dec,

language = "English",

volume = "100",

pages = "437 -- 446",

journal = "Minerva Medica",

publisher = "Edizioni Minerva Medica S.p.A.",

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TY - JOUR

T1 - Clinical guidelines for the management of acute viral infections in patients with systemic lupus erythematosus

AU - Ramos-Casals, M.

AU - Cuadrado, M. J.

AU - Alba, P.

AU - Sanna, G.

AU - Brito-Zeron, P.

AU - Bertolaccini, L.

AU - Babini, A.

AU - Moreno, A.

AU - D'Cruz, D.

AU - Khamashta, M. A.

PY - 2009/12

Y1 - 2009/12

N2 - In recent decades, many research groups have focused on the role of viral infections in the etiopathogenesis of systemic lupus erythematosus (SLE), the so-called "viral hypothesis". The main candidates are herpes viruses such as Epstein-Barr virus (EBV) and cytomegalovirus (CMV), which have a high seroprevalence in the general population. However, a viral causal agent of SLE has not yet been discovered, although many interesting clinical findings on the complex interactions between viruses and SLE have been made. This review analyzes 88 cases of acute viral infections in adult patients with SLE and identifies situations in which viral infections influenced the diagnosis, prognosis or treatment of SLE. We also propose clinical guidelines for the management of these infections in patients with SLE.

AB - In recent decades, many research groups have focused on the role of viral infections in the etiopathogenesis of systemic lupus erythematosus (SLE), the so-called "viral hypothesis". The main candidates are herpes viruses such as Epstein-Barr virus (EBV) and cytomegalovirus (CMV), which have a high seroprevalence in the general population. However, a viral causal agent of SLE has not yet been discovered, although many interesting clinical findings on the complex interactions between viruses and SLE have been made. This review analyzes 88 cases of acute viral infections in adult patients with SLE and identifies situations in which viral infections influenced the diagnosis, prognosis or treatment of SLE. We also propose clinical guidelines for the management of these infections in patients with SLE.

M3 - Literature review

VL - 100

SP - 437

EP - 446

JO - Minerva Medica

JF - Minerva Medica

IS - 6

ER -

Clinical guidelines for the management of acute viral infections in patients with systemic lupus erythematosus

Abstract

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