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Cocaine-induced disturbances of corticogenesis in the developing murine brain

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Cocaine-induced disturbances of corticogenesis in the developing murine brain. / Gressens, P; Kosofsky, B E; Evrard, P; Gressens, Pierre.

In: Neuroscience Letters, Vol. 140, No. 1, 08.06.1992, p. 113-6.

Research output: Contribution to journalArticle

Harvard

Gressens, P, Kosofsky, BE, Evrard, P & Gressens, P 1992, 'Cocaine-induced disturbances of corticogenesis in the developing murine brain', Neuroscience Letters, vol. 140, no. 1, pp. 113-6. https://doi.org/10.1016/0304-3940(92)90694-3

APA

Gressens, P., Kosofsky, B. E., Evrard, P., & Gressens, P. (1992). Cocaine-induced disturbances of corticogenesis in the developing murine brain. Neuroscience Letters, 140(1), 113-6. https://doi.org/10.1016/0304-3940(92)90694-3

Vancouver

Gressens P, Kosofsky BE, Evrard P, Gressens P. Cocaine-induced disturbances of corticogenesis in the developing murine brain. Neuroscience Letters. 1992 Jun 8;140(1):113-6. https://doi.org/10.1016/0304-3940(92)90694-3

Author

Gressens, P ; Kosofsky, B E ; Evrard, P ; Gressens, Pierre. / Cocaine-induced disturbances of corticogenesis in the developing murine brain. In: Neuroscience Letters. 1992 ; Vol. 140, No. 1. pp. 113-6.

Bibtex Download

@article{0132649cd0434ffdad9166292fa7b832,
title = "Cocaine-induced disturbances of corticogenesis in the developing murine brain",
abstract = "Exposure of fetuses to cocaine can induce behavioral disturbances and structural modifications of the CNS. Cocaine was injected into pregnant mice from the eighth day of gestation until term and the brains of their offspring were examined at the light and EM levels. Cocaine severely disturbs neocortical architecture, disrupting horizontal and vertical lamination, and inducing abnormal array of the axonal-dendritic bundles. Cocaine also alters several steps of gliogenesis. The severity of the malformations is variable, but evident in all exposed animals.",
keywords = "Animals, Antibodies, Monoclonal, Cerebral Cortex, Cocaine, Embryonic and Fetal Development, Female, Gestational Age, Glial Fibrillary Acidic Protein, Maternal-Fetal Exchange, Mice, Mice, Inbred Strains, Microscopy, Electron, Neuroglia, Neurons, Pregnancy, Reference Values",
author = "P Gressens and Kosofsky, {B E} and P Evrard and Pierre Gressens",
year = "1992",
month = jun,
day = "8",
doi = "10.1016/0304-3940(92)90694-3",
language = "English",
volume = "140",
pages = "113--6",
journal = "Neuroscience Letters",
issn = "0304-3940",
publisher = "Elsevier Ireland Ltd",
number = "1",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - Cocaine-induced disturbances of corticogenesis in the developing murine brain

AU - Gressens, P

AU - Kosofsky, B E

AU - Evrard, P

AU - Gressens, Pierre

PY - 1992/6/8

Y1 - 1992/6/8

N2 - Exposure of fetuses to cocaine can induce behavioral disturbances and structural modifications of the CNS. Cocaine was injected into pregnant mice from the eighth day of gestation until term and the brains of their offspring were examined at the light and EM levels. Cocaine severely disturbs neocortical architecture, disrupting horizontal and vertical lamination, and inducing abnormal array of the axonal-dendritic bundles. Cocaine also alters several steps of gliogenesis. The severity of the malformations is variable, but evident in all exposed animals.

AB - Exposure of fetuses to cocaine can induce behavioral disturbances and structural modifications of the CNS. Cocaine was injected into pregnant mice from the eighth day of gestation until term and the brains of their offspring were examined at the light and EM levels. Cocaine severely disturbs neocortical architecture, disrupting horizontal and vertical lamination, and inducing abnormal array of the axonal-dendritic bundles. Cocaine also alters several steps of gliogenesis. The severity of the malformations is variable, but evident in all exposed animals.

KW - Animals

KW - Antibodies, Monoclonal

KW - Cerebral Cortex

KW - Cocaine

KW - Embryonic and Fetal Development

KW - Female

KW - Gestational Age

KW - Glial Fibrillary Acidic Protein

KW - Maternal-Fetal Exchange

KW - Mice

KW - Mice, Inbred Strains

KW - Microscopy, Electron

KW - Neuroglia

KW - Neurons

KW - Pregnancy

KW - Reference Values

U2 - 10.1016/0304-3940(92)90694-3

DO - 10.1016/0304-3940(92)90694-3

M3 - Article

C2 - 1407688

VL - 140

SP - 113

EP - 116

JO - Neuroscience Letters

JF - Neuroscience Letters

SN - 0304-3940

IS - 1

ER -

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