Cognitive remediation therapy (CRT) in a specialist inpatient eating disorder service for children and adolescents: CAN-CRT study protocol for a pilot randomised controlled trial

Lucia Giombini; Sophie Nesbitt; Hannah Cox; Anna Foxall; Teo Sharia; Abigail Easter; Kate Tchanturia

doi:10.1002/erv.2592

Cognitive remediation therapy (CRT) in a specialist inpatient eating disorder service for children and adolescents: CAN-CRT study protocol for a pilot randomised controlled trial

Lucia Giombini, Sophie Nesbitt, Hannah Cox, Anna Foxall, Teo Sharia, Abigail Easter, Kate Tchanturia

Psychology Department, Rhodes Wood Hospital, Elysium Healthcare, UK.
Department of Psychological Medicine, Kings College London
Royal Holloway, University of London
Centre for Global Mental Health and Centre for Implementation Science Health Services and Population Research Department, King's College London, Institute of Psychiatry, Psychology and Neuroscience, London, UK.
Department of Psychology, Illia State University, Georgia.
SLaM South London and Maudsley NHS Foundation Trust

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Abstract

INTRODUCTION: Research on treatments for young people (YP) with anorexia nervosa (AN) is scarce. Evidence supports the use of cognitive remediation therapy (CRT) to improve central coherence and set-shifting, inefficiencies that can negatively impact on prognosis.

OBJECTIVE: The study aims to evaluate the feasibility of individual CRT in an inpatient setting for YP aged 10-18 years with AN and to qualitatively examine YP's and their parents experiences.

METHOD: In a single-centre, pilot, randomised controlled trial, 80 patients aged 10-18 years with AN will be randomly allocated to the immediate or delayed CRT group, in addition to standard treatment. A repeated measures design will be conducted across 3 time points.

DISCUSSION: The data will provide evidence regarding the feasibility of individual CRT in YP with AN, informing directions of further development of CRT. The study is in preparation for a definitive randomised controlled trial. The aim of this manuscript is to describe the study protocol.

Original language	English
Journal	European Eating Disorders Review
Early online date	26 Mar 2018
DOIs	https://doi.org/10.1002/erv.2592
Publication status	E-pub ahead of print - 26 Mar 2018

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Journal Article

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Cognitive remediation therapy (CRT)_GIOMBINI_Publishedonline26March2018_GREEN AAMAccepted author manuscript, 304 KB

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Giombini, L., Nesbitt, S., Cox, H., Foxall, A., Sharia, T., Easter, A., & Tchanturia, K. (2018). Cognitive remediation therapy (CRT) in a specialist inpatient eating disorder service for children and adolescents: CAN-CRT study protocol for a pilot randomised controlled trial. European Eating Disorders Review. Advance online publication. https://doi.org/10.1002/erv.2592

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abstract = "INTRODUCTION: Research on treatments for young people (YP) with anorexia nervosa (AN) is scarce. Evidence supports the use of cognitive remediation therapy (CRT) to improve central coherence and set-shifting, inefficiencies that can negatively impact on prognosis.OBJECTIVE: The study aims to evaluate the feasibility of individual CRT in an inpatient setting for YP aged 10-18 years with AN and to qualitatively examine YP's and their parents experiences.METHOD: In a single-centre, pilot, randomised controlled trial, 80 patients aged 10-18 years with AN will be randomly allocated to the immediate or delayed CRT group, in addition to standard treatment. A repeated measures design will be conducted across 3 time points.DISCUSSION: The data will provide evidence regarding the feasibility of individual CRT in YP with AN, informing directions of further development of CRT. The study is in preparation for a definitive randomised controlled trial. The aim of this manuscript is to describe the study protocol.",

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T2 - CAN-CRT study protocol for a pilot randomised controlled trial

AU - Giombini, Lucia

AU - Nesbitt, Sophie

AU - Cox, Hannah

AU - Foxall, Anna

AU - Sharia, Teo

AU - Easter, Abigail

AU - Tchanturia, Kate

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N2 - INTRODUCTION: Research on treatments for young people (YP) with anorexia nervosa (AN) is scarce. Evidence supports the use of cognitive remediation therapy (CRT) to improve central coherence and set-shifting, inefficiencies that can negatively impact on prognosis.OBJECTIVE: The study aims to evaluate the feasibility of individual CRT in an inpatient setting for YP aged 10-18 years with AN and to qualitatively examine YP's and their parents experiences.METHOD: In a single-centre, pilot, randomised controlled trial, 80 patients aged 10-18 years with AN will be randomly allocated to the immediate or delayed CRT group, in addition to standard treatment. A repeated measures design will be conducted across 3 time points.DISCUSSION: The data will provide evidence regarding the feasibility of individual CRT in YP with AN, informing directions of further development of CRT. The study is in preparation for a definitive randomised controlled trial. The aim of this manuscript is to describe the study protocol.

AB - INTRODUCTION: Research on treatments for young people (YP) with anorexia nervosa (AN) is scarce. Evidence supports the use of cognitive remediation therapy (CRT) to improve central coherence and set-shifting, inefficiencies that can negatively impact on prognosis.OBJECTIVE: The study aims to evaluate the feasibility of individual CRT in an inpatient setting for YP aged 10-18 years with AN and to qualitatively examine YP's and their parents experiences.METHOD: In a single-centre, pilot, randomised controlled trial, 80 patients aged 10-18 years with AN will be randomly allocated to the immediate or delayed CRT group, in addition to standard treatment. A repeated measures design will be conducted across 3 time points.DISCUSSION: The data will provide evidence regarding the feasibility of individual CRT in YP with AN, informing directions of further development of CRT. The study is in preparation for a definitive randomised controlled trial. The aim of this manuscript is to describe the study protocol.

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JO - European Eating Disorders Review

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Cognitive remediation therapy (CRT) in a specialist inpatient eating disorder service for children and adolescents: CAN-CRT study protocol for a pilot randomised controlled trial

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