Cohort profile: Demographic and clinical characteristics of the MILESTONE longitudinal cohort of young people approaching the upper age limit of their child mental health care service in Europe

Suzanne E. Gerritsen; Athanasios Maras; Larissa S. Van Bodegom; Mathilde M. Overbeek; Frank C. Verhulst; Dieter Wolke; Rebecca Appleton; Angelo Bertani; Maria G. Cataldo; Patrizia Conti; David Da Fonseca; Nikolina Davidović; Katarina Dodig-A †urković; Cecilia Ferrari; Federico Fiori; Tomislav Franić; Charlotte Gatherer; Giovanni De Girolamo; Natalie Heaney; Gaëlle Hendrickx; Alfred Kolozsvari; Flavia Micol Levi; Kate Lievesley; Jason Madan; Ottaviano Martinelli; Mathilde Mastroianni; Virginie Maurice; Fiona McNicholas; Lesley O'Hara; Moli Paul; Diane Purper-Ouakil; Veronique De Roeck; Frédérick Russet; Melanie C. Saam; Ilyas Sagar-Ouriaghli; Paramala J. Santosh; Anne Sartor; Aurélie Schandrin; Ulrike M.E. Schulze; Giulia Signorini; Swaran P. Singh; Jatinder Singh; Cathy Street; Priya Tah; Elena Tanase; Sabine Tremmery; Amanda Tuffrey; Helena Tuomainen; Therese A.M.J. Van Amelsvoort; Anna Wilson; Leanne Walker; Gwen C. Dieleman

doi:10.1136/bmjopen-2021-053373

Cohort profile: Demographic and clinical characteristics of the MILESTONE longitudinal cohort of young people approaching the upper age limit of their child mental health care service in Europe

Suzanne E. Gerritsen, Athanasios Maras, Larissa S. Van Bodegom, Mathilde M. Overbeek, Frank C. Verhulst, Dieter Wolke, Rebecca Appleton, Angelo Bertani, Maria G. Cataldo, Patrizia Conti, David Da Fonseca, Nikolina Davidović, Katarina Dodig-A †urković, Cecilia Ferrari, Federico Fiori, Tomislav Franić, Charlotte Gatherer, Giovanni De Girolamo, Natalie Heaney, Gaëlle HendrickxAlfred Kolozsvari, Flavia Micol Levi, Kate Lievesley, Jason Madan, Ottaviano Martinelli, Mathilde Mastroianni, Virginie Maurice, Fiona McNicholas, Lesley O'Hara, Moli Paul, Diane Purper-Ouakil, Veronique De Roeck, Frédérick Russet, Melanie C. Saam, Ilyas Sagar-Ouriaghli, Paramala J. Santosh, Anne Sartor, Aurélie Schandrin, Ulrike M.E. Schulze, Giulia Signorini, Swaran P. Singh, Jatinder Singh, Cathy Street, Priya Tah, Elena Tanase, Sabine Tremmery, Amanda Tuffrey, Helena Tuomainen, Therese A.M.J. Van Amelsvoort, Anna Wilson, Leanne Walker, Gwen C. Dieleman^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

Purpose The presence of distinct child and adolescent mental health services (CAMHS) and adult mental health services (AMHS) impacts continuity of mental health treatment for young people. However, we do not know the extent of discontinuity of care in Europe nor the effects of discontinuity on the mental health of young people. Current research is limited, as the majority of existing studies are retrospective, based on small samples or used non-standardised information from medical records. The MILESTONE prospective cohort study aims to examine associations between service use, mental health and other outcomes over 24 months, using information from self, parent and clinician reports. Participants Seven hundred sixty-three young people from 39 CAMHS in 8 European countries, their parents and CAMHS clinicians who completed interviews and online questionnaires and were followed up for 2 years after reaching the upper age limit of the CAMHS they receive treatment at. Findings to date This cohort profile describes the baseline characteristics of the MILESTONE cohort. The mental health of young people reaching the upper age limit of their CAMHS varied greatly in type and severity: 32.8% of young people reported clinical levels of self-reported problems and 18.6% were rated to be € markedly ill', € severely ill' or € among the most extremely ill' by their clinician. Fifty-seven per cent of young people reported psychotropic medication use in the previous half year. Future plans Analysis of longitudinal data from the MILESTONE cohort will be used to assess relationships between the demographic and clinical characteristics of young people reaching the upper age limit of their CAMHS and the type of care the young person uses over the next 2 years, such as whether the young person transitions to AMHS. At 2 years follow-up, the mental health outcomes of young people following different care pathways will be compared. Trial registration number NCT03013595.

Original language	English
Article number	053373
Journal	BMJ Open
Volume	11
Issue number	12
DOIs	https://doi.org/10.1136/bmjopen-2021-053373
Publication status	Published - 16 Dec 2021

Keywords

adult psychiatry
child & adolescent psychiatry
international health services

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1136/bmjopen-2021-053373

Cite this

Gerritsen, S. E., Maras, A., Van Bodegom, L. S., Overbeek, M. M., Verhulst, F. C., Wolke, D., Appleton, R., Bertani, A., Cataldo, M. G., Conti, P., Da Fonseca, D., Davidović, N., Dodig-A †urković, K., Ferrari, C., Fiori, F., Franić, T., Gatherer, C., De Girolamo, G., Heaney, N., ... Dieleman, G. C. (2021). Cohort profile: Demographic and clinical characteristics of the MILESTONE longitudinal cohort of young people approaching the upper age limit of their child mental health care service in Europe. BMJ Open, 11(12), Article 053373. https://doi.org/10.1136/bmjopen-2021-053373

@article{701c40215b5d48e28f20396e9e6ea803,

title = "Cohort profile: Demographic and clinical characteristics of the MILESTONE longitudinal cohort of young people approaching the upper age limit of their child mental health care service in Europe",

abstract = "Purpose The presence of distinct child and adolescent mental health services (CAMHS) and adult mental health services (AMHS) impacts continuity of mental health treatment for young people. However, we do not know the extent of discontinuity of care in Europe nor the effects of discontinuity on the mental health of young people. Current research is limited, as the majority of existing studies are retrospective, based on small samples or used non-standardised information from medical records. The MILESTONE prospective cohort study aims to examine associations between service use, mental health and other outcomes over 24 months, using information from self, parent and clinician reports. Participants Seven hundred sixty-three young people from 39 CAMHS in 8 European countries, their parents and CAMHS clinicians who completed interviews and online questionnaires and were followed up for 2 years after reaching the upper age limit of the CAMHS they receive treatment at. Findings to date This cohort profile describes the baseline characteristics of the MILESTONE cohort. The mental health of young people reaching the upper age limit of their CAMHS varied greatly in type and severity: 32.8% of young people reported clinical levels of self-reported problems and 18.6% were rated to be € markedly ill', € severely ill' or € among the most extremely ill' by their clinician. Fifty-seven per cent of young people reported psychotropic medication use in the previous half year. Future plans Analysis of longitudinal data from the MILESTONE cohort will be used to assess relationships between the demographic and clinical characteristics of young people reaching the upper age limit of their CAMHS and the type of care the young person uses over the next 2 years, such as whether the young person transitions to AMHS. At 2 years follow-up, the mental health outcomes of young people following different care pathways will be compared. Trial registration number NCT03013595.",

keywords = "adult psychiatry, child & adolescent psychiatry, international health services",

author = "Gerritsen, {Suzanne E.} and Athanasios Maras and {Van Bodegom}, {Larissa S.} and Overbeek, {Mathilde M.} and Verhulst, {Frank C.} and Dieter Wolke and Rebecca Appleton and Angelo Bertani and Cataldo, {Maria G.} and Patrizia Conti and {Da Fonseca}, David and Nikolina Davidovi{\'c} and {Dodig-A †urkovi{\'c}}, Katarina and Cecilia Ferrari and Federico Fiori and Tomislav Frani{\'c} and Charlotte Gatherer and {De Girolamo}, Giovanni and Natalie Heaney and Ga{\"e}lle Hendrickx and Alfred Kolozsvari and Levi, {Flavia Micol} and Kate Lievesley and Jason Madan and Ottaviano Martinelli and Mathilde Mastroianni and Virginie Maurice and Fiona McNicholas and Lesley O'Hara and Moli Paul and Diane Purper-Ouakil and {De Roeck}, Veronique and Fr{\'e}d{\'e}rick Russet and Saam, {Melanie C.} and Ilyas Sagar-Ouriaghli and Santosh, {Paramala J.} and Anne Sartor and Aur{\'e}lie Schandrin and Schulze, {Ulrike M.E.} and Giulia Signorini and Singh, {Swaran P.} and Jatinder Singh and Cathy Street and Priya Tah and Elena Tanase and Sabine Tremmery and Amanda Tuffrey and Helena Tuomainen and {Van Amelsvoort}, {Therese A.M.J.} and Anna Wilson and Leanne Walker and Dieleman, {Gwen C.}",

note = "Funding Information: Funding The MILESTONE project was funded by European Commission{\textquoteright}s 7th Framework Programme under grant number 602442. Publisher Copyright: {\textcopyright} 2021 Museum National d'Histoire Naturelle. All rights reserved.",

year = "2021",

month = dec,

day = "16",

doi = "10.1136/bmjopen-2021-053373",

language = "English",

volume = "11",

journal = "BMJ Open",

issn = "2044-6055",

publisher = "BMJ Publishing Group",

number = "12",

}

Gerritsen, SE, Maras, A, Van Bodegom, LS, Overbeek, MM, Verhulst, FC, Wolke, D, Appleton, R, Bertani, A, Cataldo, MG, Conti, P, Da Fonseca, D, Davidović, N, Dodig-A †urković, K, Ferrari, C, Fiori, F, Franić, T, Gatherer, C, De Girolamo, G, Heaney, N, Hendrickx, G, Kolozsvari, A, Levi, FM, Lievesley, K, Madan, J, Martinelli, O, Mastroianni, M, Maurice, V, McNicholas, F, O'Hara, L, Paul, M, Purper-Ouakil, D, De Roeck, V, Russet, F, Saam, MC, Sagar-Ouriaghli, I , Santosh, PJ, Sartor, A, Schandrin, A, Schulze, UME, Signorini, G, Singh, SP, Singh, J, Street, C, Tah, P, Tanase, E, Tremmery, S, Tuffrey, A, Tuomainen, H, Van Amelsvoort, TAMJ, Wilson, A, Walker, L & Dieleman, GC 2021, 'Cohort profile: Demographic and clinical characteristics of the MILESTONE longitudinal cohort of young people approaching the upper age limit of their child mental health care service in Europe', BMJ Open, vol. 11, no. 12, 053373. https://doi.org/10.1136/bmjopen-2021-053373

Cohort profile: Demographic and clinical characteristics of the MILESTONE longitudinal cohort of young people approaching the upper age limit of their child mental health care service in Europe. / Gerritsen, Suzanne E.; Maras, Athanasios; Van Bodegom, Larissa S. et al.
In: BMJ Open, Vol. 11, No. 12, 053373, 16.12.2021.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Cohort profile

T2 - Demographic and clinical characteristics of the MILESTONE longitudinal cohort of young people approaching the upper age limit of their child mental health care service in Europe

AU - Gerritsen, Suzanne E.

AU - Maras, Athanasios

AU - Van Bodegom, Larissa S.

AU - Overbeek, Mathilde M.

AU - Verhulst, Frank C.

AU - Wolke, Dieter

AU - Appleton, Rebecca

AU - Bertani, Angelo

AU - Cataldo, Maria G.

AU - Conti, Patrizia

AU - Da Fonseca, David

AU - Davidović, Nikolina

AU - Dodig-A †urković, Katarina

AU - Ferrari, Cecilia

AU - Fiori, Federico

AU - Franić, Tomislav

AU - Gatherer, Charlotte

AU - De Girolamo, Giovanni

AU - Heaney, Natalie

AU - Hendrickx, Gaëlle

AU - Kolozsvari, Alfred

AU - Levi, Flavia Micol

AU - Lievesley, Kate

AU - Madan, Jason

AU - Martinelli, Ottaviano

AU - Mastroianni, Mathilde

AU - Maurice, Virginie

AU - McNicholas, Fiona

AU - O'Hara, Lesley

AU - Paul, Moli

AU - Purper-Ouakil, Diane

AU - De Roeck, Veronique

AU - Russet, Frédérick

AU - Saam, Melanie C.

AU - Sagar-Ouriaghli, Ilyas

AU - Santosh, Paramala J.

AU - Sartor, Anne

AU - Schandrin, Aurélie

AU - Schulze, Ulrike M.E.

AU - Signorini, Giulia

AU - Singh, Swaran P.

AU - Singh, Jatinder

AU - Street, Cathy

AU - Tah, Priya

AU - Tanase, Elena

AU - Tremmery, Sabine

AU - Tuffrey, Amanda

AU - Tuomainen, Helena

AU - Van Amelsvoort, Therese A.M.J.

AU - Wilson, Anna

AU - Walker, Leanne

AU - Dieleman, Gwen C.

N1 - Funding Information: Funding The MILESTONE project was funded by European Commission’s 7th Framework Programme under grant number 602442. Publisher Copyright: © 2021 Museum National d'Histoire Naturelle. All rights reserved.

PY - 2021/12/16

Y1 - 2021/12/16

N2 - Purpose The presence of distinct child and adolescent mental health services (CAMHS) and adult mental health services (AMHS) impacts continuity of mental health treatment for young people. However, we do not know the extent of discontinuity of care in Europe nor the effects of discontinuity on the mental health of young people. Current research is limited, as the majority of existing studies are retrospective, based on small samples or used non-standardised information from medical records. The MILESTONE prospective cohort study aims to examine associations between service use, mental health and other outcomes over 24 months, using information from self, parent and clinician reports. Participants Seven hundred sixty-three young people from 39 CAMHS in 8 European countries, their parents and CAMHS clinicians who completed interviews and online questionnaires and were followed up for 2 years after reaching the upper age limit of the CAMHS they receive treatment at. Findings to date This cohort profile describes the baseline characteristics of the MILESTONE cohort. The mental health of young people reaching the upper age limit of their CAMHS varied greatly in type and severity: 32.8% of young people reported clinical levels of self-reported problems and 18.6% were rated to be € markedly ill', € severely ill' or € among the most extremely ill' by their clinician. Fifty-seven per cent of young people reported psychotropic medication use in the previous half year. Future plans Analysis of longitudinal data from the MILESTONE cohort will be used to assess relationships between the demographic and clinical characteristics of young people reaching the upper age limit of their CAMHS and the type of care the young person uses over the next 2 years, such as whether the young person transitions to AMHS. At 2 years follow-up, the mental health outcomes of young people following different care pathways will be compared. Trial registration number NCT03013595.

AB - Purpose The presence of distinct child and adolescent mental health services (CAMHS) and adult mental health services (AMHS) impacts continuity of mental health treatment for young people. However, we do not know the extent of discontinuity of care in Europe nor the effects of discontinuity on the mental health of young people. Current research is limited, as the majority of existing studies are retrospective, based on small samples or used non-standardised information from medical records. The MILESTONE prospective cohort study aims to examine associations between service use, mental health and other outcomes over 24 months, using information from self, parent and clinician reports. Participants Seven hundred sixty-three young people from 39 CAMHS in 8 European countries, their parents and CAMHS clinicians who completed interviews and online questionnaires and were followed up for 2 years after reaching the upper age limit of the CAMHS they receive treatment at. Findings to date This cohort profile describes the baseline characteristics of the MILESTONE cohort. The mental health of young people reaching the upper age limit of their CAMHS varied greatly in type and severity: 32.8% of young people reported clinical levels of self-reported problems and 18.6% were rated to be € markedly ill', € severely ill' or € among the most extremely ill' by their clinician. Fifty-seven per cent of young people reported psychotropic medication use in the previous half year. Future plans Analysis of longitudinal data from the MILESTONE cohort will be used to assess relationships between the demographic and clinical characteristics of young people reaching the upper age limit of their CAMHS and the type of care the young person uses over the next 2 years, such as whether the young person transitions to AMHS. At 2 years follow-up, the mental health outcomes of young people following different care pathways will be compared. Trial registration number NCT03013595.

KW - adult psychiatry

KW - child & adolescent psychiatry

KW - international health services

UR - http://www.scopus.com/inward/record.url?scp=85122137578&partnerID=8YFLogxK

U2 - 10.1136/bmjopen-2021-053373

DO - 10.1136/bmjopen-2021-053373

M3 - Article

AN - SCOPUS:85122137578

SN - 2044-6055

VL - 11

JO - BMJ Open

JF - BMJ Open

IS - 12

M1 - 053373

ER -

Cohort profile: Demographic and clinical characteristics of the MILESTONE longitudinal cohort of young people approaching the upper age limit of their child mental health care service in Europe

Abstract

Keywords

UN SDGs

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