King's College London

Research portal

Cohort profile of the South London and Maudsley NHS Foundation Trust Biomedical Research Centre (SLaM BRC) Case Register: current status and recent enhancement of an Electronic Mental Health Record-derived data resource

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Article numbere008721
Pages (from-to)1-22
Number of pages22
JournalBMJ Open
Issue number3
Accepted/In press26 Nov 2015
Published3 Mar 2016


  • BMJ Open-2016-Perera-

    BMJ_Open_2016_Perera_.pdf, 3.66 MB, application/pdf

    Uploaded date:02 Mar 2016

    Version:Final published version

    Licence:CC BY

King's Authors


Purpose: The South London and Maudsley National Health Service (NHS) Foundation Trust Biomedical Research Centre (SLaM BRC) Case Register and its
Clinical Record Interactive Search (CRIS) application were developed in 2008, generating a research repository of real-time, anonymised, structured and
open-text data derived from the electronic health record system used by SLaM, a large mental healthcare provider in southeast London. In this paper, we update
this register’s descriptive data, and describe the substantial expansion and extension of the data resource since its original development.
Participants: Descriptive data were generated from the SLaM BRC Case Register on 31 December 2014. Currently, there are over 250 000 patient records accessed through CRIS.
Findings to date: Since 2008, the most significant developments in the SLaM BRC Case Register have been the introduction of natural language processing to
extract structured data from open-text fields, linkages to external sources of data, and the addition of a parallel relational database (Structured Query
Language) output. Natural language processing applications to date have brought in new and hitherto inaccessible data on cognitive function, education,
social care receipt, smoking, diagnostic statements and pharmacotherapy. In addition, through external data linkages, large volumes of supplementary information have been accessed on mortality, hospital attendances
and cancer registrations.
Future plans: Coupled with robust data security and governance structures, electronic health records provide potentially transformative information on
mental disorders and outcomes in routine clinical care. The SLaM BRC Case Register continues to grow as a database, with approximately 20 000 new cases added each year, in addition to extension of follow-up for existing cases. Data linkages and natural language processing present important opportunities to
enhance this type of research resource further, achieving both volume and depth of data. However, research projects still need to be carefully tailored, so that they take into account the nature and quality of the source information.

Download statistics

No data available

View graph of relations

© 2020 King's College London | Strand | London WC2R 2LS | England | United Kingdom | Tel +44 (0)20 7836 5454