Colchicine: An effective treatment for refractory malignant pericardial effusion

T Ng, A Gatt, A Pagliuca, G J Mufti

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


We report a patient with AL amyloidosis and chemoresistant light-chain multiple myeloma who developed a progressive malignant pericardial effusion leading to cardiac tamponade. Despite pericardiocentesis and surgical intervention, the pericardial effusion failed to resolve. The administration of oral colchicine produced symptomatic relief within 5 days, with the resolution of pericardial effusion after 14 days of treatment. As the administration of colchicine is simple and the side-effect is usually minimal, further studies are warranted to establish the feasibility of using colchicine to treat malignant pericardial effusion. Copyright (C) 2001 S. Karger AG, Basel.
Original languageEnglish
Pages (from-to)217 - 219
Number of pages3
JournalActa Haematologica
Issue number4
Publication statusPublished - 2000


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