Combined Quantitative T2* Map and Structural T2-Weighted Tissue-Specific Analysis for Fetal Brain MRI: Pilot Automated Pipeline

Alena U. Uus*, Megan Hall, Kelly Payette, Joseph V. Hajnal, Maria Deprez, Mary A. Rutherford, Jana Hutter, Lisa Story

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference paperpeer-review

1 Citation (Scopus)

Abstract

Over the past decade, automated 3D reconstruction and segmentation has been widely applied to processing and analysis of fetal MRI. While the majority of reported methods primarily focus on structural brain imaging, additional quantitative T2* information could improve characterisation of changes in functional tissue properties. In this work, we propose a first solution for automated combined tissue-specific analysis of 3D quantitative T2* map and structural T2-weighted (T2w) fetal brain MRI. We build upon the existing 3D structural brain analysis pipeline from SVRTK by adding fully automated 3D T2* reconstructions globally aligned to 3D segmented T2w images (already reconstructed in the standard radiological space) followed by deep learning T2* tissue parcellation. In addition, we assess the general applicability the proposed pipeline by analysing brain growth trajectories in 26 control T2w+T2* fetal MRI datasets from 20–28 weeks GA range.

Original languageEnglish
Title of host publicationPerinatal, Preterm and Paediatric Image Analysis - 8th International Workshop, PIPPI 2023, Held in Conjunction with MICCAI 2023, Proceedings
EditorsDaphna Link-Sourani, Esra Abaci Turk, Christopher Macgowan, Jana Hutter, Jana Hutter, Andrew Melbourne, Roxane Licandro, Roxane Licandro
PublisherSpringer Science and Business Media Deutschland GmbH
Pages28-38
Number of pages11
ISBN (Print)9783031455438
DOIs
Publication statusPublished - 2023
Event8th International Workshop on Perinatal, Preterm and Paediatric Image Analysis, PIPPI 2023 - Vancouver, Canada
Duration: 12 Oct 202312 Oct 2023

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume14246 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference8th International Workshop on Perinatal, Preterm and Paediatric Image Analysis, PIPPI 2023
Country/TerritoryCanada
CityVancouver
Period12/10/202312/10/2023

Keywords

  • Automated segmentation
  • Brain T2*
  • Fetal MRI
  • Multi-contrast alignment
  • Tissue parcellation

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