Commentary: Biological embedding of childhood adversity: where do we go from here? A reflection on Koss and Gunnar (2018)

Andrea Danese*

*Corresponding author for this work

Research output: Contribution to journalComment/debatepeer-review

8 Citations (Scopus)

Abstract

The review by Koss & Gunna provides a scholarly overview of the role of the hypothalamic-pituitary-adrenal (HPA) axis in mediating the association between childhood adversity and psychopathology. Through their insightful observations, the authors craft a rich framework to critically appraise the current evidence and inform future research in this area. Overall, the review calls for a new generation of studies testing biological embedding hypotheses with greater attention to design, measurement, statistical models, and translational approaches. These new studies are much needed. By uncovering the causal pathways underlying the biological embedding of childhood adversity, we can gain important new tools to prevent the most impairing forms of psychopathology among the most vulnerable individuals in society.

Original languageEnglish
Pages (from-to)347-349
Number of pages3
JournalJournal of Child Psychology and Psychiatry and Allied Disciplines
Volume59
Issue number4
Early online date25 Mar 2018
DOIs
Publication statusPublished - 1 Apr 2018

Keywords

  • Adversity

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