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Common brain disorders are associated with heritable patterns of apparent aging of the brain

Research output: Contribution to journalArticle

Karolinska Schizophrenia Project (KaSP)

Original languageEnglish
Pages (from-to)1617-1623
Number of pages7
JournalNature Neuroscience
Volume22
Issue number10
DOIs
Publication statusPublished - 1 Oct 2019

King's Authors

Abstract

Common risk factors for psychiatric and other brain disorders are likely to converge on biological pathways influencing the development and maintenance of brain structure and function across life. Using structural MRI data from 45,615 individuals aged 3-96 years, we demonstrate distinct patterns of apparent brain aging in several brain disorders and reveal genetic pleiotropy between apparent brain aging in healthy individuals and common brain disorders.

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