TY - JOUR
T1 - Common perinatal mental disorders and post-infancy child development in rural Ethiopia
T2 - a population-based cohort study
AU - Alexandra Dunn, Julia
AU - Medhin, Girmay
AU - Dewey, Michael
AU - Alem, Atalay
AU - Worku, Bogale
AU - Paksarian, Diana
AU - Newton, Charles R
AU - Tomlinson, Mark
AU - Prince, Martin
AU - Hanlon, Charlotte
N1 - Funding Information:
The authors acknowledge all the women who gave their time to participate in the original study and all Bayley scale administrators’ work. We are grateful to all data collectors, investigators, and research assistants in Ethiopia who supported data collection for the ‐ study. The study was funded through two Wellcome Trust grants: a research training fellowship for Dr Charlotte Hanlon (GR071643) and a project grant (GR081504). The Wellcome Trust did not have any role in the study design, data collection, analysis, and interpretation of data, in the writing of the manuscript, or in the decision to submit the manuscript for publication. C.H. is funded by the National Institute of Health Research (NIHR) Global Health Research Unit on Health System Strengthening in Sub‐Saharan Africa, King’s College London (GHRU 16/136/54), and an NIHR RIGHT grant (NIHR200842) using U.K. aid from the U.K. Government. C.H. receives support from AMARI as part of the DELTAS Africa Initiative [DEL‐15‐01]. C MaMiE
Funding Information:
The authors acknowledge all the women who gave their time to participate in the original study and all Bayley scale administrators? work. We are grateful to all data collectors, investigators, and research assistants in Ethiopia who supported data collection for the C-MaMiE study. The study was funded through two Wellcome Trust grants: a research training fellowship for Dr Charlotte Hanlon (GR071643) and a project grant (GR081504). The Wellcome Trust did not have any role in the study design, data collection, analysis, and interpretation of data, in the writing of the manuscript, or in the decision to submit the manuscript for publication. C.H. is funded by the National Institute of Health Research (NIHR) Global Health Research Unit on Health System Strengthening in Sub-Saharan Africa, King?s College London (GHRU 16/136/54), and an NIHR RIGHT grant (NIHR200842) using U.K. aid from the U.K. Government. C.H. receives support from AMARI as part of the DELTAS Africa Initiative [DEL-15-01].
Publisher Copyright:
© 2022 The Authors Tropical Medicine & International Health Published by John Wiley & Sons Ltd.
PY - 2022/3
Y1 - 2022/3
N2 - Objective: To investigate whether maternal common mental disorders (CMD) in the postnatal period are prospectively associated with child development at 2.5 and 3.5 years in a rural low-income African setting. Methods: This study was nested within the C-MaMiE (Child outcomes in relation to Maternal Mental health in Ethiopia) population-based cohort in Butajira, Ethiopia, and conducted from 2005 to 2006. The sample comprised of 496 women who had recently given birth to living, singleton babies with recorded birth weight measurements, who were 15 to 44 years of age, and residing in six rural sub-districts. Postnatal CMD measurements were ascertained 2 months after delivery. Language, cognitive, and motor development were obtained from the child 2.5 and 3.5 years after birth using a locally adapted version of the Bayley Scales of Infant Development (3rd Ed). Maternal CMD symptoms were measured using a locally validated WHO Self-Reporting Questionnaire. A linear mixed-effects regression model was used to analyze the relationship between postnatal CMD and child development. Results: After adjusting for confounders, there was no evidence for an association between postnatal CMD and overall child development or the cognitive sub-domain in the preschool period. There was no evidence of effect modification by levels of social support, socioeconomic status, stunting, or sex of the child. Conclusions: Previous studies from predominantly urban and peri-urban settings in middle-income countries have established a relationship between maternal CMD and child development, which contrasts with the findings from this study. The risk and protective factors for child development may differ in areas characterized by high social adversity and food insecurity. More studies are needed to investigate maternal CMD’s impact on child development in low-resource and rural areas.
AB - Objective: To investigate whether maternal common mental disorders (CMD) in the postnatal period are prospectively associated with child development at 2.5 and 3.5 years in a rural low-income African setting. Methods: This study was nested within the C-MaMiE (Child outcomes in relation to Maternal Mental health in Ethiopia) population-based cohort in Butajira, Ethiopia, and conducted from 2005 to 2006. The sample comprised of 496 women who had recently given birth to living, singleton babies with recorded birth weight measurements, who were 15 to 44 years of age, and residing in six rural sub-districts. Postnatal CMD measurements were ascertained 2 months after delivery. Language, cognitive, and motor development were obtained from the child 2.5 and 3.5 years after birth using a locally adapted version of the Bayley Scales of Infant Development (3rd Ed). Maternal CMD symptoms were measured using a locally validated WHO Self-Reporting Questionnaire. A linear mixed-effects regression model was used to analyze the relationship between postnatal CMD and child development. Results: After adjusting for confounders, there was no evidence for an association between postnatal CMD and overall child development or the cognitive sub-domain in the preschool period. There was no evidence of effect modification by levels of social support, socioeconomic status, stunting, or sex of the child. Conclusions: Previous studies from predominantly urban and peri-urban settings in middle-income countries have established a relationship between maternal CMD and child development, which contrasts with the findings from this study. The risk and protective factors for child development may differ in areas characterized by high social adversity and food insecurity. More studies are needed to investigate maternal CMD’s impact on child development in low-resource and rural areas.
UR - http://www.scopus.com/inward/record.url?scp=85124547222&partnerID=8YFLogxK
U2 - 10.1111/tmi.13725
DO - 10.1111/tmi.13725
M3 - Article
C2 - 35080279
SN - 1365-3156
VL - 27
SP - 251
EP - 261
JO - Tropical Medicine & International Health
JF - Tropical Medicine & International Health
IS - 3
ER -
