King's College London

Research portal

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

Research output: Contribution to journalArticle

Paul Hollingworth, Denise Harold, Rebecca Sims, Amy Gerrish, Jean-Charles Lambert, Minerva M. Carrasquillo, Richard Abraham, Marian L. Hamshere, Jaspreet Singh Pahwa, Valentina Moskvina, Kimberley Dowzell, Nicola Jones, Alexandra Stretton, Charlene Thomas, Alex Richards, Dobril Ivanov, Caroline Widdowson, Jade Chapman, Simon Lovestone, John Powell & 152 more Petroula Proitsi, Michelle K. Lupton, Carol Brayne, David C. Rubinsztein, Michael Gill, Brian Lawlor, Aoibhinn Lynch, Kristelle S. Brown, Peter A. Passmore, David Craig, Bernadette McGuinness, Stephen Todd, Clive Holmes, David Mann, A. David Smith, Helen Beaumont, Donald Warden, Gordon Wilcock, Seth Love, Patrick G. Kehoe, Nigel M. Hooper, Emma R. L. C. Vardy, John Hardy, Simon Mead, Nick C. Fox, Martin Rossor, John Collinge, Wolfgang Maier, Frank Jessen, Eckart Ruether, Britta Schuermann, Reiner Heun, Heike Koelsch, Hendrik van den Bussche, Isabella Heuser, Johannes Kornhuber, Jens Wiltfang, Martin Dichgans, Lutz Froelich, Harald Hampel, John Gallacher, Michael Huell, Dan Rujescu, Ina Giegling, Alison M. Goate, John S. K. Kauwe, Carlos Cruchaga, Petra Nowotny, John C. Morris, Kevin Mayo, Kristel Sleegers, Karolien Bettens, Sebastiaan Engelborghs, Peter P. De Deyn, Christine Van Broeckhoven, Gill Livingston, Nicholas J. Bass, Hugh Gurling, Andrew McQuillin, Rhian Gwilliam, Panagiotis Deloukas, Ammar Al-Chalabi, Christopher E. Shaw, Magda Tsolaki, Andrew B. Singleton, Rita Guerreiro, Thomas W. Muehleisen, Markus M. Noethen, Susanne Moebus, Karl-Heinz Joeckel, Norman Klopp, H-Erich Wichmann, V. Shane Pankratz, Sigrid B. Sando, Jan O. Aasly, Maria Barcikowska, Zbigniew K. Wszolek, Dennis W. Dickson, Neill R. Graff-Radford, Ronald C. Petersen, Cornelia M. van Duijn, Monique M. B. Breteler, M. Arfan Ikram, Anita L. DeStefano, Annette L. Fitzpatrick, Oscar Lopez, Lenore J. Launer, Sudha Seshadri, Claudine Berr, Dominique Campion, Jacques Epelbaum, Jean-Francois Dartigues, Christophe Tzourio, Annick Alperovitch, Mark Lathrop, Thomas M. Feulner, Patricia Friedrich, Caterina Riehle, Michael Krawczak, Stefan Schreiber, Manuel Mayhaus, S. Nicolhaus, Stefan Wagenpfeil, Stacy Steinberg, Hreinn Stefansson, Kari Stefansson, Jon Snaedal, Sigurbjorn Bjornsson, Palmi V. Jonsson, Vincent Chouraki, Benjamin Genier-Boley, Mikko Hiltunen, Hilkka Soininen, Onofre Combarros, Diana Zelenika, Marc Delepine, Maria J. Bullido, Florence Pasquier, Ignacio Mateo, Ana Frank-Garcia, Elisa Porcellini, Olivier Hanon, Eliecer Coto, Victoria Alvarez, Paolo Bosco, Gabriele Siciliano, Michelangelo Mancuso, Francesco Panza, Vincenzo Solfrizzi, Benedetta Nacmias, Sandro Sorbi, Paola Bossu, Paola Piccardi, Beatrice Arosio, Giorgio Annoni, Davide Seripa, Alberto Pilotto, Elio Scarpini, Daniela Galimberti, Alexis Brice, Didier Hannequin, Federico Licastro, Lesley Jones, Peter A. Holmans, Thorlakur Jonsson, Matthias Riemenschneider, Kevin Morgan, Steven G. Younkin, Michael J. Owen, Michael O'Donovan, Philippe Amouyel, Julie Williams

Original languageEnglish
Pages (from-to)429-435
Number of pages7
JournalNature Genetics
Volume43
Issue number5
DOIs
Publication statusPublished - May 2011

Documents

King's Authors

Abstract

We sought to identify new susceptibility loci for Alzheimer's disease through a staged association study (GERAD+) and by testing suggestive loci reported by the Alzheimer's Disease Genetic Consortium (ADGC) in a companion paper. We undertook a combined analysis of four genome-wide association datasets (stage 1) and identified ten newly associated variants with P

Download statistics

No data available

View graph of relations

© 2018 King's College London | Strand | London WC2R 2LS | England | United Kingdom | Tel +44 (0)20 7836 5454