Comparative efficacy of three forms of parenteral iron

Richard Dillon; Ibrahim Momoh; Yvonne Francis; Laura Cameron; Claire N Harrison; Deepti Radia

doi:10.1155/2012/473514

Comparative efficacy of three forms of parenteral iron

Richard Dillon, Ibrahim Momoh, Yvonne Francis, Laura Cameron, Claire N Harrison, Deepti Radia

Comprehensive Cancer Centre

GSTT Guy's and St Thomas' NHS Foundation Trust

Research output: Contribution to journal › Article › peer-review

Abstract

Intravenous iron therapy is a useful treatment for the rapid correction of iron deficiency anaemia and can be used to avoid or reduce the requirement for allogeneic blood transfusion. Several intravenous iron preparations are available commercially which differ in cost, mode of administration and side effect profile. There are few data directly comparing the efficacy of these preparations. In this retrospective single-centre study, we present the results from two hundred and eight patients treated using three different iron preparations (iron dextran, iron sucrose and ferric carboxymaltose) and compare the effect on haemoglobin levels and other measures of iron deficiency six weeks after treatment. Within the limitations of our study design, we show a statistically and clinically significant difference in efficacy between these preparations.

Original language	English
Pages (from-to)	473514
Journal	Journal of blood transfusion
Volume	2012
DOIs	https://doi.org/10.1155/2012/473514
Publication status	Published - 2012

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10.1155/2012/473514

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title = "Comparative efficacy of three forms of parenteral iron",

abstract = "Intravenous iron therapy is a useful treatment for the rapid correction of iron deficiency anaemia and can be used to avoid or reduce the requirement for allogeneic blood transfusion. Several intravenous iron preparations are available commercially which differ in cost, mode of administration and side effect profile. There are few data directly comparing the efficacy of these preparations. In this retrospective single-centre study, we present the results from two hundred and eight patients treated using three different iron preparations (iron dextran, iron sucrose and ferric carboxymaltose) and compare the effect on haemoglobin levels and other measures of iron deficiency six weeks after treatment. Within the limitations of our study design, we show a statistically and clinically significant difference in efficacy between these preparations. ",

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AU - Momoh, Ibrahim

AU - Francis, Yvonne

AU - Cameron, Laura

AU - Harrison, Claire N

AU - Radia, Deepti

PY - 2012

Y1 - 2012

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AB - Intravenous iron therapy is a useful treatment for the rapid correction of iron deficiency anaemia and can be used to avoid or reduce the requirement for allogeneic blood transfusion. Several intravenous iron preparations are available commercially which differ in cost, mode of administration and side effect profile. There are few data directly comparing the efficacy of these preparations. In this retrospective single-centre study, we present the results from two hundred and eight patients treated using three different iron preparations (iron dextran, iron sucrose and ferric carboxymaltose) and compare the effect on haemoglobin levels and other measures of iron deficiency six weeks after treatment. Within the limitations of our study design, we show a statistically and clinically significant difference in efficacy between these preparations.

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DO - 10.1155/2012/473514

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SN - 2090-9187

VL - 2012

SP - 473514

JO - Journal of blood transfusion

JF - Journal of blood transfusion

ER -

Comparative efficacy of three forms of parenteral iron

Abstract

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