Comparison of two different sites of measurement for transabdominal uterine artery Doppler velocimetry at 11-13 weeks

TY - JOUR

T1 - Comparison of two different sites of measurement for transabdominal uterine artery Doppler velocimetry at 11-13 weeks

AU - Lefebvre, J.

AU - Demers, S.

AU - Bujold, E.

AU - Nicolaides, K. H.

AU - Girard, M.

AU - Brassard, N.

AU - Audibert, F.

PY - 2012/9

Y1 - 2012/9

N2 - Objectives: To compare the feasibility of two transabdominal approaches for performing first-trimester uterine artery (UtA) Doppler and to evaluate the correlation with pulsatility index (PI) in the second trimester.  Methods: This was a prospective longitudinal Doppler study of the uterine arteries at 1113 and 2122 weeks' gestation. Transabdominal ultrasound and color Doppler were used to measure the UtA-PI of the ascending branch of the uterine artery at the level of the internal cervical os (Site A) and at the level of the apparent crossover with the external iliac artery (Site B) at 1113 weeks, and at Site B only at 2122 weeks. In all cases the measured left and right PI were converted to a multiple of the median (MoM) for gestational age, and the intercorrelation between the measurements at different sites and gestational ages was calculated using non-parametric analysis (Spearman's rank correlation).  Results: Satisfactory measurements were obtained at 1113 weeks from both uterine arteries in all 81 women at Site A and in 50 (62%; 95% CI, 5072%) at Site B (P < 0.01). Measurements were obtained at Site B at 2122 weeks in all cases. In the 50 cases with measurements from both sites at 1113 weeks, the correlation of PI-MoMs between Sites A and B at 1113 weeks was only moderate (? = 0.61). The correlation between first-trimester UtA-PI MoMs at Site A and second-trimester UtA-PI MoMs was stronger than that between first-trimester UtA-PI MoMs at Site B and second-trimester UtA-PI MoMs (? = 0.73 vs ? = 0.47, P < 0.01).  Conclusion: Evaluation of UtA-PI at 1113 weeks can be achieved at the level of the internal cervical os in a greater proportion of women than at the level of the apparent crossover with the external iliac vessels, and the measurements obtained correlate better with second-trimester UtA-PI. Copyright (C) 2012 ISUOG. Published by John Wiley & Sons, Ltd.

AB - Objectives: To compare the feasibility of two transabdominal approaches for performing first-trimester uterine artery (UtA) Doppler and to evaluate the correlation with pulsatility index (PI) in the second trimester.  Methods: This was a prospective longitudinal Doppler study of the uterine arteries at 1113 and 2122 weeks' gestation. Transabdominal ultrasound and color Doppler were used to measure the UtA-PI of the ascending branch of the uterine artery at the level of the internal cervical os (Site A) and at the level of the apparent crossover with the external iliac artery (Site B) at 1113 weeks, and at Site B only at 2122 weeks. In all cases the measured left and right PI were converted to a multiple of the median (MoM) for gestational age, and the intercorrelation between the measurements at different sites and gestational ages was calculated using non-parametric analysis (Spearman's rank correlation).  Results: Satisfactory measurements were obtained at 1113 weeks from both uterine arteries in all 81 women at Site A and in 50 (62%; 95% CI, 5072%) at Site B (P < 0.01). Measurements were obtained at Site B at 2122 weeks in all cases. In the 50 cases with measurements from both sites at 1113 weeks, the correlation of PI-MoMs between Sites A and B at 1113 weeks was only moderate (? = 0.61). The correlation between first-trimester UtA-PI MoMs at Site A and second-trimester UtA-PI MoMs was stronger than that between first-trimester UtA-PI MoMs at Site B and second-trimester UtA-PI MoMs (? = 0.73 vs ? = 0.47, P < 0.01).  Conclusion: Evaluation of UtA-PI at 1113 weeks can be achieved at the level of the internal cervical os in a greater proportion of women than at the level of the apparent crossover with the external iliac vessels, and the measurements obtained correlate better with second-trimester UtA-PI. Copyright (C) 2012 ISUOG. Published by John Wiley & Sons, Ltd.

U2 - 10.1002/uog.11137

DO - 10.1002/uog.11137

M3 - Article

SN - 0960-7692

VL - 40

SP - 288

EP - 292

JO - Ultrasound in Obstetrics and Gynecology

JF - Ultrasound in Obstetrics and Gynecology

IS - 3

ER -