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Compassionate Use of Cefiderocol as Adjunctive Treatment of Native Aortic Valve Endocarditis Due to Extremely Drug-resistant Pseudomonas aeruginosa

Research output: Contribution to journalArticlepeer-review

Jonathan D. Edgeworth, Domenico Merante, Sanjay Patel, Christopher Young, Paul Jones, Seema Vithlani, Duncan Wyncoll, Peter Roberts, Andrew Jones, Tsutae Den Nagata, Mari Ariyasu, David M. Livermore, Richard Beale

Original languageEnglish
Pages (from-to)1932-1934
Number of pages3
JournalClinical infectious diseases : an official publication of the Infectious Diseases Society of America
Issue number11
Accepted/In press8 Nov 2018
Published12 Dec 2018

King's Authors


Serious infections such as endocarditis due to extremely drug-resistance gram-negative bacteria are an increasing challenge. Here, we present successful adjunctive use of cefiderocol for a patient with persistently bacteremic healthcare-associated native aortic valve endocarditis due to an extended-spectrum beta-lactamase-positive Pseudomonas aeruginosa susceptible in vitro only to colistin, following failure of conventional therapeutic options.

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