Compressed opiate withdrawal syndrome and naltrexone

M Farrell; J Strang

doi:10.1177/026988119500900414

Compressed opiate withdrawal syndrome and naltrexone

M Farrell^*, J Strang

^*Corresponding author for this work

Research output: Contribution to journal › Comment/debate › peer-review

7 Citations (Scopus)

Abstract

The oral opiate antagonist naltrexone is in regular use in clinical practice with abstinent opiate-dependent individuals. Acute opioid withdrawal is a well-recognised consequence of consuming naltrexone while opiate dependent. Two cases of naltrexone-induced opiate withdrawal are reported. The compressed nature of the withdrawal syndrome in both of these cases and the implications for the management of protracted withdrawal symptoms are discussed. The theoretical implications of this experimental and clinical phenomenon are reviewed.

Original language	English
Article number	N/A
Pages (from-to)	383-385
Number of pages	3
Journal	Journal of Psychopharmacology
Volume	9
Issue number	4
DOIs	https://doi.org/10.1177/026988119500900414
Publication status	Published - Jul 1995

Keywords

naltrexone
opioid withdrawal
naloxone-compressed withdrawal
acute withdrawal
case report
OPIOID PHYSICAL-DEPENDENCE
METHADONE
HUMANS
CLONIDINE
SYMPTOMS
EXPOSURE
ADDICTS

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10.1177/026988119500900414

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title = "Compressed opiate withdrawal syndrome and naltrexone",

abstract = "The oral opiate antagonist naltrexone is in regular use in clinical practice with abstinent opiate-dependent individuals. Acute opioid withdrawal is a well-recognised consequence of consuming naltrexone while opiate dependent. Two cases of naltrexone-induced opiate withdrawal are reported. The compressed nature of the withdrawal syndrome in both of these cases and the implications for the management of protracted withdrawal symptoms are discussed. The theoretical implications of this experimental and clinical phenomenon are reviewed.",

keywords = "naltrexone, opioid withdrawal, naloxone-compressed withdrawal, acute withdrawal, case report, OPIOID PHYSICAL-DEPENDENCE, METHADONE, HUMANS, CLONIDINE, SYMPTOMS, EXPOSURE, ADDICTS",

author = "M Farrell and J Strang",

year = "1995",

month = jul,

doi = "10.1177/026988119500900414",

language = "English",

volume = "9",

pages = "383--385",

journal = "Journal of Psychopharmacology",

issn = "0269-8811",

publisher = "SAGE Publications Ltd STM",

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TY - JOUR

T1 - Compressed opiate withdrawal syndrome and naltrexone

AU - Farrell, M

AU - Strang, J

PY - 1995/7

Y1 - 1995/7

N2 - The oral opiate antagonist naltrexone is in regular use in clinical practice with abstinent opiate-dependent individuals. Acute opioid withdrawal is a well-recognised consequence of consuming naltrexone while opiate dependent. Two cases of naltrexone-induced opiate withdrawal are reported. The compressed nature of the withdrawal syndrome in both of these cases and the implications for the management of protracted withdrawal symptoms are discussed. The theoretical implications of this experimental and clinical phenomenon are reviewed.

AB - The oral opiate antagonist naltrexone is in regular use in clinical practice with abstinent opiate-dependent individuals. Acute opioid withdrawal is a well-recognised consequence of consuming naltrexone while opiate dependent. Two cases of naltrexone-induced opiate withdrawal are reported. The compressed nature of the withdrawal syndrome in both of these cases and the implications for the management of protracted withdrawal symptoms are discussed. The theoretical implications of this experimental and clinical phenomenon are reviewed.

KW - naltrexone

KW - opioid withdrawal

KW - naloxone-compressed withdrawal

KW - acute withdrawal

KW - case report

KW - OPIOID PHYSICAL-DEPENDENCE

KW - METHADONE

KW - HUMANS

KW - CLONIDINE

KW - SYMPTOMS

KW - EXPOSURE

KW - ADDICTS

U2 - 10.1177/026988119500900414

DO - 10.1177/026988119500900414

M3 - Comment/debate

SN - 0269-8811

VL - 9

SP - 383

EP - 385

JO - Journal of Psychopharmacology

JF - Journal of Psychopharmacology

IS - 4

M1 - N/A

ER -

Compressed opiate withdrawal syndrome and naltrexone

Abstract

Keywords

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