Concise synthesis of taxol A-ring components: Remote diastereoselective additions of alkenyl lithiums to aldehydes

Christopher Frost, Patrick Linnane, Philip Magnus*, Mark Spyvee

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)

Abstract

The acid chloride 6 provides access to 7 (R,S and S,S) which upon bromine-lithium exchange undergoes remarkably highly diastereoselective additions to aldehydes; 7 is also readily elaborated into the acetal 10.

Original languageEnglish
Pages (from-to)9139-9142
Number of pages4
JournalTETRAHEDRON LETTERS
Volume37
Issue number51
DOIs
Publication statusPublished - 16 Dec 1996

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